Methyltransferase-like proteins in cancer biology and potential therapeutic targeting.
Cancer biology
METTLs
Methyltransferase
Molecular mechanism
Therapeutics
Journal
Journal of hematology & oncology
ISSN: 1756-8722
Titre abrégé: J Hematol Oncol
Pays: England
ID NLM: 101468937
Informations de publication
Date de publication:
02 08 2023
02 08 2023
Historique:
received:
10
03
2023
accepted:
10
07
2023
medline:
4
8
2023
pubmed:
3
8
2023
entrez:
2
8
2023
Statut:
epublish
Résumé
RNA modification has recently become a significant process of gene regulation, and the methyltransferase-like (METTL) family of proteins plays a critical role in RNA modification, methylating various types of RNAs, including mRNA, tRNA, microRNA, rRNA, and mitochondrial RNAs. METTL proteins consist of a unique seven-beta-strand domain, which binds to the methyl donor SAM to catalyze methyl transfer. The most typical family member METTL3/METTL14 forms a methyltransferase complex involved in N6-methyladenosine (m6A) modification of RNA, regulating tumor proliferation, metastasis and invasion, immunotherapy resistance, and metabolic reprogramming of tumor cells. METTL1, METTL4, METTL5, and METTL16 have also been recently identified to have some regulatory ability in tumorigenesis, and the rest of the METTL family members rely on their methyltransferase activity for methylation of different nucleotides, proteins, and small molecules, which regulate translation and affect processes such as cell differentiation and development. Herein, we summarize the literature on METTLs in the last three years to elucidate their roles in human cancers and provide a theoretical basis for their future use as potential therapeutic targets.
Identifiants
pubmed: 37533128
doi: 10.1186/s13045-023-01477-7
pii: 10.1186/s13045-023-01477-7
pmc: PMC10394802
doi:
Substances chimiques
Methyltransferases
EC 2.1.1.-
Adenosine
K72T3FS567
MicroRNAs
0
METTL3 protein, human
EC 2.1.1.62
METTL16 protein, human
EC 2.1.1.-
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
89Informations de copyright
© 2023. The Author(s).
Références
Mol Ther. 2023 Jun 7;31(6):1596-1614
pubmed: 35965412
Theranostics. 2022 Aug 29;12(14):6291-6307
pubmed: 36168624
Front Oncol. 2022 Jun 22;12:914692
pubmed: 35814454
Sci Rep. 2018 Mar 28;8(1):5311
pubmed: 29593291
Int J Biol Sci. 2022 Jun 3;18(9):3874-3887
pubmed: 35813476
Life (Basel). 2021 Oct 21;11(11):
pubmed: 34832997
J Hematol Oncol. 2020 Aug 27;13(1):117
pubmed: 32854717
Nat Commun. 2022 Mar 18;13(1):1478
pubmed: 35304469
Cancer Cell. 2021 Jul 12;39(7):945-957.e10
pubmed: 34019807
Cell Biol Toxicol. 2022 Aug 15;:
pubmed: 35971034
Carcinogenesis. 2022 Jun 4;43(5):419-429
pubmed: 35136989
Nucleic Acids Res. 2020 Sep 18;48(16):9250-9261
pubmed: 32813009
Cell Metab. 2021 Jun 1;33(6):1221-1233.e11
pubmed: 33910046
J Cell Biochem. 2017 Sep;118(9):2587-2598
pubmed: 28247949
Theranostics. 2021 Jun 11;11(16):7640-7657
pubmed: 34335955
Cell Rep. 2020 Dec 22;33(12):108544
pubmed: 33357433
Cancer Cell. 2020 Mar 16;37(3):270-288
pubmed: 32183948
J Biol Chem. 2015 Jan 2;290(1):423-34
pubmed: 25416781
Mol Cell. 2016 Jul 21;63(2):306-317
pubmed: 27373337
Gastroenterology. 2022 Oct;163(4):891-907
pubmed: 35700773
Nat Commun. 2021 Feb 9;12(1):891
pubmed: 33563959
Cell Res. 2017 Oct;27(10):1216-1230
pubmed: 28914256
Cell Death Dis. 2021 Dec 17;13(1):3
pubmed: 34916487
Proc Natl Acad Sci U S A. 2021 Aug 31;118(35):
pubmed: 34452996
Front Cell Dev Biol. 2022 Jan 12;9:784719
pubmed: 35096816
Clin Epigenetics. 2021 Sep 16;13(1):173
pubmed: 34530916
Cell Rep. 2022 Oct 25;41(4):111530
pubmed: 36288719
Mol Cancer. 2020 Aug 25;19(1):130
pubmed: 32843065
Front Cell Dev Biol. 2021 Mar 04;9:650023
pubmed: 33748145
Genes Dis. 2020 Jul 17;9(1):268-274
pubmed: 35005123
Int J Biochem Cell Biol. 2020 May;122:105731
pubmed: 32097728
Nature. 2022 Dec;612(7938):141-147
pubmed: 36352227
J Clin Endocrinol Metab. 2022 Jan 18;107(2):474-490
pubmed: 34562008
Cell. 2019 Jan 24;176(3):491-504.e21
pubmed: 30612740
Redox Biol. 2021 Nov;47:102151
pubmed: 34607160
Cell Res. 2021 Mar;31(3):345-361
pubmed: 32859993
J Biol Chem. 2020 Jun 19;295(25):8505-8513
pubmed: 32371392
Cancers (Basel). 2022 Oct 20;14(20):
pubmed: 36291932
Mol Ther. 2021 Dec 1;29(12):3422-3435
pubmed: 34371184
Signal Transduct Target Ther. 2020 Dec 26;5(1):296
pubmed: 33361765
Nature. 2020 Dec;588(7839):712-716
pubmed: 33328633
Oncogene. 2022 Mar;41(11):1622-1633
pubmed: 35094011
Cancer Sci. 2023 Mar;114(3):837-854
pubmed: 36382580
Adv Biol (Weinh). 2021 Mar;5(3):e1900311
pubmed: 33729699
Mol Cell. 2021 Aug 19;81(16):3323-3338.e14
pubmed: 34352207
Biol Chem. 2020 Oct 19;402(1):89-98
pubmed: 33544495
J Biol Chem. 2016 Apr 29;291(18):9581-95
pubmed: 26929405
Phytomedicine. 2022 Jan;94:153823
pubmed: 34763315
Mol Cell. 2021 Aug 19;81(16):3339-3355.e8
pubmed: 34352206
Cell Death Dis. 2022 Apr 18;13(4):358
pubmed: 35436987
J Exp Clin Cancer Res. 2022 Jan 25;41(1):36
pubmed: 35078505
Clin Transl Med. 2021 Sep;11(9):e545
pubmed: 34586732
Mol Ther Oncolytics. 2022 Jun 07;26:27-34
pubmed: 35784404
Protein Cell. 2021 Dec;12(12):965-970
pubmed: 34218407
Mol Cancer. 2020 Oct 29;19(1):152
pubmed: 33121495
Nucleic Acids Res. 2020 May 21;48(9):5157-5168
pubmed: 32266935
Nucleic Acids Res. 2021 Apr 6;49(6):3185-3203
pubmed: 33693809
Front Genet. 2020 Oct 02;11:540186
pubmed: 33133142
Cell Death Discov. 2022 Apr 8;8(1):179
pubmed: 35396379
Wiley Interdiscip Rev RNA. 2022 Mar;13(2):e1681
pubmed: 34227247
Mol Ther. 2021 May 5;29(5):1821-1837
pubmed: 33484966
PLoS Biol. 2022 Jul 19;20(7):e3001683
pubmed: 35853000
Leukemia. 2022 Nov;36(11):2586-2595
pubmed: 36266324
Nature. 2021 May;593(7860):597-601
pubmed: 33902106
Oncogene. 2022 Apr;41(14):2069-2078
pubmed: 35177812
Cell Death Dis. 2022 Aug 19;13(8):723
pubmed: 35985997
Commun Biol. 2021 Dec 3;4(1):1361
pubmed: 34862464
Nat Cell Biol. 2022 Feb;24(2):205-216
pubmed: 35145225
Cell Death Dis. 2022 Nov 24;13(11):992
pubmed: 36424383
EMBO J. 2021 Mar 1;40(5):e106309
pubmed: 33459381
Cancer Gene Ther. 2023 Jan;30(1):209-218
pubmed: 36195720
Cell Death Differ. 2021 Jun;28(6):1773-1789
pubmed: 33328570
Mol Oncol. 2020 Jun;14(6):1282-1296
pubmed: 32216017
Cell Death Dis. 2022 Jul 28;13(7):657
pubmed: 35902569
Cell Death Differ. 2022 Mar;29(3):627-641
pubmed: 34608273
PLoS Pathog. 2019 Jun 21;15(6):e1007796
pubmed: 31226160
Ann Transl Med. 2022 Aug;10(16):895
pubmed: 36110989
Nucleic Acids Res. 2019 Nov 4;47(19):10267-10281
pubmed: 31665743
Cell Death Dis. 2022 May 21;13(5):483
pubmed: 35595748
J Hematol Oncol. 2021 Apr 13;14(1):60
pubmed: 33849617
Angiogenesis. 2021 Feb;24(1):83-96
pubmed: 32920668
Hepatology. 2023 Jun 1;77(6):1896-1910
pubmed: 35698894
Int J Oral Sci. 2021 Aug 11;13(1):26
pubmed: 34381012
Stem Cell Reports. 2018 Jun 5;10(6):1807-1820
pubmed: 29706498
Eur J Pharmacol. 2020 Jul 15;879:173134
pubmed: 32339511
Drug Deliv. 2022 Dec;29(1):1257-1271
pubmed: 35467477
Mol Ther Nucleic Acids. 2021 Dec 11;27:577-592
pubmed: 35036067
Oncogene. 2022 Apr;41(15):2239-2253
pubmed: 35217794
Surg Radiol Anat. 2022 Apr;44(4):599-608
pubmed: 35218407
Front Pharmacol. 2020 Feb 28;11:178
pubmed: 32180726
Front Oncol. 2021 Aug 11;11:696371
pubmed: 34458141
Mol Cancer. 2022 May 10;21(1):111
pubmed: 35538475
Cancer Cell Int. 2022 Jan 7;22(1):11
pubmed: 34996469
Oncogene. 2022 Jun;41(23):3197-3209
pubmed: 35501461
Cancer Lett. 2021 Oct 10;518:214-229
pubmed: 34298122
Cancer Lett. 2023 Jan 28;553:215971
pubmed: 36257380
Gastroenterology. 2021 Mar;160(4):1284-1300.e16
pubmed: 33217448
J Transl Med. 2022 Oct 20;20(1):476
pubmed: 36266694
Nucleic Acids Res. 2022 Jan 11;50(1):449-457
pubmed: 34908152
Cell Death Dis. 2022 May 14;13(5):463
pubmed: 35568711
Nat Commun. 2022 Mar 10;13(1):1248
pubmed: 35273176
J Exp Clin Cancer Res. 2022 Jan 3;41(1):4
pubmed: 34980213
Open Biol. 2017 Sep;7(9):
pubmed: 28878038
J Exp Clin Cancer Res. 2021 Feb 9;40(1):62
pubmed: 33563300
J Cancer Res Clin Oncol. 2023 Jul;149(8):5095-5108
pubmed: 36348020
Br J Cancer. 2022 Jul;127(1):30-42
pubmed: 35249103
Front Genet. 2017 Mar 28;8:31
pubmed: 28400788
Gut. 2020 Jul;69(7):1193-1205
pubmed: 31582403
Cell Mol Gastroenterol Hepatol. 2022;13(4):1223-1242
pubmed: 34952201
Nat Rev Mol Cell Biol. 2019 Oct;20(10):608-624
pubmed: 31520073
Nat Commun. 2022 Jun 1;13(1):3061
pubmed: 35650238
Mol Cell. 2018 Sep 20;71(6):986-1000.e11
pubmed: 30197299
EMBO Rep. 2020 Jul 3;21(7):e49443
pubmed: 32350990
Cell Death Discov. 2022 Mar 30;8(1):143
pubmed: 35354789
Aging (Albany NY). 2020 Nov 20;12(23):23931-23944
pubmed: 33237039
Gynecol Oncol. 2020 Apr;157(1):268-279
pubmed: 31955862
Clin Transl Med. 2022 May;12(5):e778
pubmed: 35522946
Mol Ther. 2022 Feb 2;30(2):932-946
pubmed: 34547464
EMBO Rep. 2020 Oct 5;21(10):e49863
pubmed: 32783360
Front Oncol. 2021 Apr 29;11:650534
pubmed: 33996568
Nat Cancer. 2022 Sep;3(9):1088-1104
pubmed: 36138131
Cell Death Dis. 2021 Jun 15;12(6):617
pubmed: 34131102
Nat Rev Genet. 2015 Feb;16(2):98-112
pubmed: 25534324
Theranostics. 2022 Jun 13;12(10):4802-4817
pubmed: 35832094
Nat Cancer. 2022 Sep;3(9):1018-1020
pubmed: 36138137
Mol Cell. 2022 Mar 17;82(6):1156-1168.e7
pubmed: 35219383
Int J Oncol. 2022 Sep;61(3):
pubmed: 35856434
Front Immunol. 2022 Aug 26;13:976107
pubmed: 36091006
J Biol Chem. 2014 Aug 29;289(35):24640-51
pubmed: 25023281
EMBO J. 2020 Oct 15;39(20):e104514
pubmed: 32964498
Oncogene. 2021 Apr;40(16):2968-2981
pubmed: 33758320
Front Immunol. 2022 Jan 27;13:845193
pubmed: 35154166
Int J Mol Sci. 2022 Sep 29;23(19):
pubmed: 36232810
Cancer Cell. 2019 Apr 15;35(4):677-691.e10
pubmed: 30991027
Dev Cell. 2022 Jun 20;57(12):1466-1481.e6
pubmed: 35659339
Cell Death Discov. 2021 Sep 8;7(1):237
pubmed: 34497267
J Cell Mol Med. 2022 May;26(9):2505-2519
pubmed: 35348293
Cancer Gene Ther. 2022 Jul;29(7):1043-1055
pubmed: 35022519
J Mol Evol. 2002 Oct;55(4):431-44
pubmed: 12355263
Mol Cell. 2022 Jul 7;82(13):2370-2384.e10
pubmed: 35512709
Stem Cell Res Ther. 2020 Jul 22;11(1):306
pubmed: 32698871
J Biol Chem. 2017 Oct 27;292(43):17950-17962
pubmed: 28887308
Clin Transl Med. 2022 Nov;12(11):e1107
pubmed: 36354136
Cell Biol Toxicol. 2022 Jan 17;:
pubmed: 35038059
Nat Commun. 2022 Oct 28;13(1):6435
pubmed: 36307435
Pharmaceuticals (Basel). 2022 Apr 01;15(4):
pubmed: 35455436
EBioMedicine. 2022 Aug;82:104142
pubmed: 35810559
J Hazard Mater. 2022 Sep 5;437:129310
pubmed: 35749893
J Transl Med. 2022 Jan 29;20(1):51
pubmed: 35093098
Mol Oncol. 2022 May;16(9):1841-1856
pubmed: 35048498
Int J Biol Sci. 2022 Apr 24;18(7):3048-3065
pubmed: 35541914
Sci Adv. 2020 Aug 26;6(35):eaaz4551
pubmed: 32923617
Genomics. 1999 May 1;57(3):424-8
pubmed: 10329009
Int J Oncol. 2022 Jan;60(1):
pubmed: 34913069
Nat Cell Biol. 2022 Aug;24(8):1278-1290
pubmed: 35927451
Hepatology. 2018 Jun;67(6):2254-2270
pubmed: 29171881
Int J Mol Sci. 2021 Feb 22;22(4):
pubmed: 33671635
Mol Cell. 2022 May 5;82(9):1660-1677.e10
pubmed: 35320754
Cell Death Dis. 2020 Oct 24;11(10):911
pubmed: 33099572
Clin Transl Med. 2022 Jun;12(6):e906
pubmed: 35678231
Mol Cancer. 2020 Feb 28;19(1):46
pubmed: 32111213
J Transl Med. 2022 Jul 6;20(1):298
pubmed: 35794583
PLoS Genet. 2022 Oct 26;18(10):e1010366
pubmed: 36288387
FASEB J. 2019 Nov;33(11):13040-13050
pubmed: 31487196
EMBO Rep. 2017 Nov;18(11):2004-2014
pubmed: 29051200
RNA. 1997 Nov;3(11):1233-47
pubmed: 9409616
Phytother Res. 2022 Jun;36(6):2542-2557
pubmed: 35443090
N Engl J Med. 2017 Apr 20;376(16):1540-1550
pubmed: 28423296
RNA Biol. 2022 Jan;19(1):751-763
pubmed: 35638109
Nat Genet. 2022 Sep;54(9):1427-1437
pubmed: 36071173
Mol Cancer. 2022 Feb 23;21(1):60
pubmed: 35197058
Int J Biol Sci. 2022 May 1;18(8):3223-3236
pubmed: 35637959
Mol Cancer. 2020 Apr 3;19(1):72
pubmed: 32245489
J Cell Mol Med. 2021 Jul;25(14):6602-6617
pubmed: 34075693
EMBO J. 2020 Jun 17;39(12):e103181
pubmed: 32368828
J Exp Clin Cancer Res. 2021 Mar 6;40(1):90
pubmed: 33676554
Mol Cell Proteomics. 2011 Jan;10(1):M110.000976
pubmed: 20930037
Cancer Lett. 2021 Jul 28;511:36-46
pubmed: 33933553
J Hematol Oncol. 2019 Dec 9;12(1):135
pubmed: 31818312
Cell Death Dis. 2020 Nov 11;11(11):969
pubmed: 33177491
Nature. 2010 Apr 22;464(7292):1205-9
pubmed: 20376003
J Exp Clin Cancer Res. 2022 Jan 10;41(1):19
pubmed: 35012593
Cancer Sci. 2022 Nov;113(11):3787-3800
pubmed: 35984699
J Dent Res. 2022 May;101(5):580-589
pubmed: 34796755
Elife. 2022 Jun 08;11:
pubmed: 35674491
Cancer Gene Ther. 2022 Jul;29(7):1012-1020
pubmed: 34799724
Bioact Mater. 2022 Nov 09;23:69-79
pubmed: 36406251
Cancer Res. 2021 Jun 1;81(11):2847-2860
pubmed: 33795252
Mol Cancer. 2022 Feb 14;21(1):51
pubmed: 35164771
Elife. 2022 May 03;11:
pubmed: 35502895
Clin Transl Med. 2021 Sep;11(9):e553
pubmed: 34586728
Genome Biol. 2022 Dec 2;23(1):249
pubmed: 36461076
Mol Cell. 2019 Jun 20;74(6):1278-1290.e9
pubmed: 31031083
Oncogene. 2022 Mar;41(12):1742-1751
pubmed: 35121826
Mol Cell. 2021 Dec 2;81(23):4810-4825.e12
pubmed: 34774131
J Exp Clin Cancer Res. 2021 Apr 15;40(1):132
pubmed: 33858476
Cell Death Discov. 2022 Apr 26;8(1):229
pubmed: 35474040
J Mol Med (Berl). 2022 Dec;100(12):1771-1785
pubmed: 36352154
BMC Med. 2021 Nov 22;19(1):284
pubmed: 34802443
Nat Commun. 2018 Aug 24;9(1):3411
pubmed: 30143613
Cancer Res. 2020 Sep 15;80(18):3945-3958
pubmed: 32680921
Cell Mol Biol Lett. 2022 May 20;27(1):41
pubmed: 35596159
FEBS Lett. 2017 Jun;591(12):1641-1652
pubmed: 28391595
J Transl Med. 2021 May 13;19(1):209
pubmed: 33985542
Hepatology. 2023 Apr 1;77(4):1122-1138
pubmed: 35598182
Int J Mol Sci. 2022 Jun 09;23(12):
pubmed: 35742899
Genome Biol. 2021 Jan 28;22(1):51
pubmed: 33509238
Mol Ther. 2022 Jun 1;30(6):2342-2353
pubmed: 35192934
Cancer Sci. 2023 Jan;114(1):105-114
pubmed: 36114749
J Transl Med. 2022 Jun 27;20(1):288
pubmed: 35761379
Int J Mol Sci. 2021 Dec 18;22(24):
pubmed: 34948388
Sci Rep. 2021 Mar 9;11(1):5459
pubmed: 33750817
Oncogene. 2022 Sep;41(39):4420-4432
pubmed: 35987795
Front Pharmacol. 2022 Oct 20;13:1002565
pubmed: 36386128
Nat Cell Biol. 2021 Apr;23(4):355-365
pubmed: 33795874
J Hematol Oncol. 2021 Nov 10;14(1):190
pubmed: 34758859
Cancer Res. 2022 May 3;82(9):1789-1802
pubmed: 35502544
Mol Ther Oncolytics. 2021 Jul 21;22:574-581
pubmed: 34589576
Int J Oncol. 2022 Jan;60(1):
pubmed: 34970694
Exp Hematol. 2005 Jan;33(1):85-93
pubmed: 15661401
Zhonghua Yu Fang Yi Xue Za Zhi. 2021 Aug 6;55(8):983-989
pubmed: 34445837
Proc Natl Acad Sci U S A. 2016 Dec 6;113(49):14013-14018
pubmed: 27872311
Cancer Sci. 2021 Aug;112(8):3243-3254
pubmed: 34097350
Mol Cell. 2020 May 7;78(3):382-395.e8
pubmed: 32183942
Oncogene. 2023 Jan;42(5):374-388
pubmed: 36473908
Cancer Res. 2021 Jul 15;81(14):3822-3834
pubmed: 33903120
Mol Cancer. 2019 Jun 22;18(1):110
pubmed: 31228940
Theranostics. 2021 Jan 26;11(8):3676-3693
pubmed: 33664855
Mol Cancer. 2020 Jun 17;19(1):106
pubmed: 32552762
Int J Mol Sci. 2022 Jan 19;23(3):
pubmed: 35162982
Cancer Gene Ther. 2021 Apr;28(3-4):335-349
pubmed: 32939058
Nature. 2016 May 25;534(7608):575-8
pubmed: 27281194
Front Genet. 2020 Dec 10;11:604597
pubmed: 33362863
Cell Mol Life Sci. 2022 Feb 18;79(3):135
pubmed: 35179655
Nucleic Acids Res. 2020 Sep 4;48(15):8576-8590
pubmed: 32761127
Genes Dev. 2020 May 1;34(9-10):715-729
pubmed: 32217665
Pharmacol Res. 2021 Oct;172:105814
pubmed: 34450313
Front Immunol. 2022 Mar 31;13:795240
pubmed: 35432338
Mol Ther. 2020 Dec 2;28(12):2593-2604
pubmed: 32956623
Oncogene. 2022 Aug;41(35):4145-4158
pubmed: 35869392
Cell Death Dis. 2022 Aug 17;13(8):715
pubmed: 35977935
J Hematol Oncol. 2021 Jul 10;14(1):109
pubmed: 34246306
Cell. 2018 Jan 11;172(1-2):90-105.e23
pubmed: 29249359
Drug Dev Res. 2022 May;83(3):783-799
pubmed: 35040501
Am J Cancer Res. 2022 Feb 15;12(2):893-906
pubmed: 35261810
Front Pharmacol. 2022 Apr 27;13:878135
pubmed: 35571106
Mol Cancer. 2021 Aug 20;20(1):105
pubmed: 34416901
EMBO J. 2005 May 4;24(9):1696-705
pubmed: 15861136
Int J Biol Macromol. 2022 Dec 31;223(Pt A):916-930
pubmed: 36375665
Bioengineered. 2021 Dec;12(1):3159-3176
pubmed: 34187307
Cancer Res. 2023 Jan 4;83(1):89-102
pubmed: 36102722
Front Oncol. 2021 Jun 17;11:615296
pubmed: 34221955
Nat Commun. 2021 Sep 17;12(1):5522
pubmed: 34535671
Mol Cancer. 2019 Jun 24;18(1):112
pubmed: 31230592
Adv Sci (Weinh). 2022 Oct;9(28):e2201889
pubmed: 35975461
Cell Stem Cell. 2018 Feb 1;22(2):191-205.e9
pubmed: 29290617
Nucleic Acids Res. 2022 Nov 11;50(20):11619-11634
pubmed: 36399511
ChemMedChem. 2020 May 6;15(9):744-748
pubmed: 32159918
Nucleic Acids Res. 2022 Apr 22;50(7):4012-4028
pubmed: 35357504
J Cell Biol. 2005 Dec 19;171(6):1023-34
pubmed: 16365168
Gut. 2023 Aug;72(8):1555-1567
pubmed: 36283801
Mol Cancer. 2019 Oct 13;18(1):142
pubmed: 31607270
Commun Biol. 2022 Sep 5;5(1):908
pubmed: 36064747
iScience. 2020 Mar 27;23(3):100968
pubmed: 32199293
BMC Cancer. 2017 Feb 20;17(1):145
pubmed: 28219369
Biochem Biophys Res Commun. 2022 Jan 22;589:159-164
pubmed: 34922197
Clin Transl Med. 2021 Dec;11(12):e661
pubmed: 34898034
Cell Rep. 2017 Mar 14;18(11):2622-2634
pubmed: 28297667
Nat Commun. 2022 Sep 26;13(1):5636
pubmed: 36163360
Front Immunol. 2021 Aug 03;12:719628
pubmed: 34413861
Cell Death Differ. 2019 Nov;26(11):2268-2283
pubmed: 30778199
Cell Death Dis. 2022 Mar 12;13(3):230
pubmed: 35279688
Mol Cancer. 2022 Feb 10;21(1):43
pubmed: 35144642
Cancers (Basel). 2022 Nov 14;14(22):
pubmed: 36428672
Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):20159-20170
pubmed: 32747553
Mol Cell. 2021 Dec 2;81(23):4765-4767
pubmed: 34861186
Nucleic Acids Res. 2021 Aug 20;49(14):8309-8323
pubmed: 34268557
Nat Rev Mol Cell Biol. 2020 Mar;21(3):167-178
pubmed: 32005969
Int J Mol Sci. 2022 Aug 25;23(17):
pubmed: 36077054
Autophagy. 2023 Jan;19(1):360-362
pubmed: 35574843
Cancer Lett. 2021 Dec 1;522:44-56
pubmed: 34530048
Mol Cell. 2016 May 5;62(3):335-345
pubmed: 27117702
ChemMedChem. 2021 Oct 6;16(19):3035-3043
pubmed: 34237194
Cancer Commun (Lond). 2022 Mar;42(3):223-244
pubmed: 35179319
Stem Cell Reports. 2022 Aug 9;17(8):1799-1809
pubmed: 35947961
Clin Transl Med. 2021 Dec;11(12):e675
pubmed: 34936728
Int Immunopharmacol. 2022 Jun;107:108586
pubmed: 35228032
Nat Commun. 2021 Dec 10;12(1):7213
pubmed: 34893641
Cell Commun Signal. 2022 Mar 19;20(1):36
pubmed: 35305660
Cell Mol Gastroenterol Hepatol. 2021;12(3):839-856
pubmed: 33992834
Oncogene. 2020 Jul;39(31):5358-5372
pubmed: 32576970
Nucleic Acids Res. 2021 Jul 21;49(13):7239-7255
pubmed: 34023900
Theranostics. 2020 Apr 27;10(13):5671-5686
pubmed: 32483411
Cell Death Dis. 2021 Sep 24;12(10):870
pubmed: 34561421
Aging Cell. 2021 Feb;20(2):e13298
pubmed: 33440070
Signal Transduct Target Ther. 2021 Feb 27;6(1):89
pubmed: 33637677