The DOTA macrocyclic cavity in metallic radiopharmaceuticals: Mythology or reality?

DOTA Macrocyclic cavity Macrocyclic effect Macrocyclic ligands Metallic radiopharmaceuticals

Journal

EJNMMI radiopharmacy and chemistry
ISSN: 2365-421X
Titre abrégé: EJNMMI Radiopharm Chem
Pays: England
ID NLM: 101714628

Informations de publication

Date de publication:
03 Aug 2023
Historique:
received: 31 05 2023
accepted: 31 07 2023
medline: 3 8 2023
pubmed: 3 8 2023
entrez: 3 8 2023
Statut: epublish

Résumé

The hypothetical concept of 'macrocyclic cavity' is largely employed as useful model to interpret the affinity of metal ions for the macrocyclic chelating ligand 2,2',2'',2'''-(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl)tetraacetic acid (H Based on X-ray structural data of metallic complexes formed by the ligand H Application of Euclidean geometry to calculate bond angles in the coordination complex of the ligand H

Sections du résumé

BACKGROUND BACKGROUND
The hypothetical concept of 'macrocyclic cavity' is largely employed as useful model to interpret the affinity of metal ions for the macrocyclic chelating ligand 2,2',2'',2'''-(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl)tetraacetic acid (H
RESULTS RESULTS
Based on X-ray structural data of metallic complexes formed by the ligand H
CONCLUSIONS CONCLUSIONS
Application of Euclidean geometry to calculate bond angles in the coordination complex of the ligand H

Identifiants

pubmed: 37535275
doi: 10.1186/s41181-023-00202-6
pii: 10.1186/s41181-023-00202-6
pmc: PMC10400501
doi:

Types de publication

Journal Article

Langues

eng

Pagination

17

Informations de copyright

© 2023. Springer Nature Switzerland AG.

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Auteurs

Adriano Duatti (A)

Department of Chemical and Pharmaceutical Sciences, University of Ferrara, Via L. Borsari, 46, 44121, Ferrara, Italy. dta@unife.it.

Classifications MeSH