Oral phytochemicals as photoprotectants in UVR exposed hairless mice: A study of hesperidin methyl chalcone, phloroglucinol, and syringic acid.
Hairless mice
Oral delivery
Photoprotection
Phytochemicals
Skin cancer
Ultraviolet radiation
Journal
Journal of photochemistry and photobiology. B, Biology
ISSN: 1873-2682
Titre abrégé: J Photochem Photobiol B
Pays: Switzerland
ID NLM: 8804966
Informations de publication
Date de publication:
Sep 2023
Sep 2023
Historique:
received:
28
06
2023
accepted:
21
07
2023
medline:
1
9
2023
pubmed:
3
8
2023
entrez:
3
8
2023
Statut:
ppublish
Résumé
Ultraviolet radiation is the primary risk factor for keratinocyte carcinoma. Because of increasing incidence rates, new methods of photoprotection must be explored. Oral supplementation with photoprotective compounds presents a promising alternative. Phytochemical compounds like hesperidin methyl chalcone, phloroglucinol, and syringic acid are particularly of interest because of their antioxidant properties. Our primary outcome was to evaluate the effects of oral phytochemicals on photocarcinogenesis with time until tumour onset as the primary endpoint. A total of 125 hairless C3.Cg-Hr
Identifiants
pubmed: 37535996
pii: S1011-1344(23)00114-8
doi: 10.1016/j.jphotobiol.2023.112760
pii:
doi:
Substances chimiques
syringic acid
E390O181H5
Phloroglucinol
DHD7FFG6YS
hesperidin methylchalcone
4T2GVA922X
Chalcones
0
Hesperidin
E750O06Y6O
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
112760Informations de copyright
Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.