Liver Transplantation for Colorectal Liver Metastases: Is It Appropriate?

Colorectal liver metastases Liver transplant Living-donor liver transplant Transplant oncology

Journal

Advances in surgery
ISSN: 1878-0555
Titre abrégé: Adv Surg
Pays: United States
ID NLM: 0045335

Informations de publication

Date de publication:
09 2023
Historique:
medline: 7 8 2023
pubmed: 4 8 2023
entrez: 3 8 2023
Statut: ppublish

Résumé

Colorectal cancer with liver metastases is a condition with significant morbidity and mortality that affects many people around the world. Many treatments exist to target liver metastases, including surgical resection, chemotherapy, nonsurgical liver-directed therapies, and liver transplantation. The field of transplant oncology is emerging as a promising alternative to palliative chemotherapy alone in appropriately selected patients. Though few clinical trials have been completed to evaluate safety of liver transplant for colorectal cancer metastases, there are several ongoing trials to hopefully make transplant a viable option for more patients with limited options.

Identifiants

pubmed: 37536852
pii: S0065-3411(23)00004-0
doi: 10.1016/j.yasu.2023.04.001
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

171-185

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Jenna N Whitrock (JN)

University of Cincinnati College of Medicine, Department of Surgery, Division of Transplantation, 231 Albert Sabin Way, Medical Science Building Room 1555, Cincinnati, OH 45267-0558. Electronic address: whitroja@ucmail.uc.edu.

Stephen J Hartman (SJ)

University of Cincinnati College of Medicine, Department of Surgery, Division of Transplantation, 231 Albert Sabin Way, Medical Science Building Room 1555, Cincinnati, OH 45267-0558.

Ralph C Quillin (RC)

University of Cincinnati College of Medicine, Department of Surgery, Division of Transplantation, 231 Albert Sabin Way, Medical Science Building Room 1555, Cincinnati, OH 45267-0558.

Shimul A Shah (SA)

University of Cincinnati College of Medicine, Department of Surgery, Division of Transplantation, 231 Albert Sabin Way, Medical Science Building Room 1555, Cincinnati, OH 45267-0558.

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Classifications MeSH