Challenges in Diagnosing and Reporting Cholangiocarcinoma.

Bile duct hamartoma Biliary duct adenoma Cholangiocarcinoma Intrahepatic Large duct type iCCA Small duct type iCCA cHCC-CCA iCCA

Journal

Surgical pathology clinics
ISSN: 1875-9157
Titre abrégé: Surg Pathol Clin
Pays: United States
ID NLM: 101491209

Informations de publication

Date de publication:
Sep 2023
Historique:
medline: 7 8 2023
pubmed: 4 8 2023
entrez: 3 8 2023
Statut: ppublish

Résumé

Intrahepatic cholangiocarcinoma is a challenge to the practicing surgical pathologist for several reasons. It is rare in many parts of the world, and thus practical exposure may be limited. Related to the fact of its rarity is the fact that more common tumors which frequently metastasize to the liver can be morphologically indistinguishable (eg, pancreatic ductal adenocarcinoma). Immunohistochemical testing is generally non-contributory in this context. Other difficulties arise from the protean morphologic manifestations of cholangiocarcinoma (ie, small duct vs. large duct) and the existence of combined cholangiocarcinoma and hepatocellular carcinoma. These, and other issues of concern to the practicing diagnostic pathologist are discussed herein.

Identifiants

pubmed: 37536891
pii: S1875-9181(23)00038-7
doi: 10.1016/j.path.2023.04.012
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

599-608

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Tony El Jabbour (T)

West Virginia University.

Attila Molnar (A)

Mount Sinai Morningside and Mount Sinai West, Department of Pathology, 1000 Tenth Avenue, First floor, Room G183, New York, NY 10019, USA.

Stephen M Lagana (SM)

New York-Presbyterian /Columbia University, Irving Medical Center, 622 W168th St, Vc14-209, New York, NY 10032, USA. Electronic address: sml2179@cumc.columbia.edu.

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Classifications MeSH