Biological markers of disease activity in inflammatory bowel diseases.

biomarkers elafin faecal calprotectin haptoglobin inflammatory bowel disease zonulin

Journal

Przeglad gastroenterologiczny
ISSN: 1895-5770
Titre abrégé: Prz Gastroenterol
Pays: Poland
ID NLM: 101280380

Informations de publication

Date de publication:
2023
Historique:
received: 02 08 2022
accepted: 02 08 2022
medline: 4 8 2023
pubmed: 4 8 2023
entrez: 4 8 2023
Statut: ppublish

Résumé

Inflammatory bowel diseases (IBD) are chronic intestinal conditions of multifactorial aetiology including genetic susceptibility, immunological impairment, dysbiosis, and environmental factors. The diagnosis is based on both clinical and endoscopic features, wherein histopathological evaluation remains a gold diagnostic standard. However, fast, reliable, and non-invasive biological markers have been used for years for diagnosis as well as for disease activity monitoring. Currently, commonly used faecal calprotectin is the only biomarker approved and recommended by the European Crohn's and Colitis Organization (ECCO). Nonetheless, other biological markers discriminating between functional and organic bowel conditions have been widely studied. Therefore, the aim of this manuscript was to review new potential biomarkers of inflammation in IBD. The aim of this study was to review currently available biomarkers of intestinal inflammation and increased gut permeability in IBD.

Identifiants

pubmed: 37538284
doi: 10.5114/pg.2023.129412
pii: 51066
pmc: PMC10395055
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

141-147

Informations de copyright

Copyright © 2023 Termedia.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

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Auteurs

Edyta Szymanska (E)

Department of Gastroenterology, Hepatology, Feeding Disorders, and Paediatrics, The Children's Memorial Health Institute, Warsaw, Poland.

Sylwia Szymanska (S)

Department of Gastroenterology, Hepatology, Feeding Disorders, and Paediatrics, The Children's Memorial Health Institute, Warsaw, Poland.

Maciej Dadalski (M)

Department of Gastroenterology, Hepatology, Feeding Disorders, and Paediatrics, The Children's Memorial Health Institute, Warsaw, Poland.

Jaroslaw Kierkus (J)

Department of Gastroenterology, Hepatology, Feeding Disorders, and Paediatrics, The Children's Memorial Health Institute, Warsaw, Poland.

Classifications MeSH