GABAergic modulation of sleep-wake states.

Humans Sleep Wakefulness GABAergic Neurons Central Nervous System Receptors, GABA-A gamma-Aminobutyric Acid
GABA Preoptic area Sleep Ventral tegmental area Wakefulness

Journal

Pharmacology & therapeutics
ISSN: 1879-016X
Titre abrégé: Pharmacol Ther
Pays: England
ID NLM: 7905840

Informations de publication

Date de publication:
09 2023
Historique:
received: 14 06 2023
revised: 24 07 2023
accepted: 31 07 2023
medline: 28 8 2023
pubmed: 5 8 2023
entrez: 4 8 2023
Statut: ppublish

Résumé

Benzodiazepine, a classical medication utilized in the treatment of insomnia, operates by augmenting the activity of the GABA

Identifiants

DOI: 10.1016/j.pharmthera.2023.108505 PMID: 37541595
pubmed: 37541595
pii: S0163-7258(23)00169-9
doi: 10.1016/j.pharmthera.2023.108505
pii:
doi:

Substances chimiques

Receptors, GABA-A 0
gamma-Aminobutyric Acid 56-12-2

Types de publication

Journal Article Review Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

108505

Informations de copyright

Copyright © 2023. Published by Elsevier Inc.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Yo Oishi (Y)

International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan; Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan.

Yuki C Saito (YC)

International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan; Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan.

Takeshi Sakurai (T)

International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan; Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan. Electronic address: sakurai.takeshi.gf@u.tsukuba.ac.jp.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › GABAergic modulation of sleep-wake states.
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Sommeil › GABAergic modulation of sleep-wake states.
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Éveil › Vigilance › GABAergic modulation of sleep-wake states.
questionsmedicales.fr › Cellules › Neurones › Neurones GABAergiques › GABAergic modulation of sleep-wake states.
questionsmedicales.fr › Système nerveux › Système nerveux central › GABAergic modulation of sleep-wake states.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs aux neuromédiateurs › Récepteurs aux acides aminés › Récepteurs GABA › Récepteurs GABA-A › GABAergic modulation of sleep-wake states.
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Amino-butyrates › Acide gamma-amino-butyrique › GABAergic modulation of sleep-wake states.