Modelling of microbial interactions in anaerobic digestion: from black to glass box.


Journal

Current opinion in microbiology
ISSN: 1879-0364
Titre abrégé: Curr Opin Microbiol
Pays: England
ID NLM: 9815056

Informations de publication

Date de publication:
10 2023
Historique:
received: 16 03 2023
revised: 20 05 2023
accepted: 10 07 2023
medline: 18 9 2023
pubmed: 6 8 2023
entrez: 5 8 2023
Statut: ppublish

Résumé

Anaerobic and microaerophilic environments are pervasive in nature, providing essential contributions to the maintenance of human health, biogeochemical cycles and the Earth's climate. These ecological niches are characterised by low free oxygen and oxidants, or lack thereof. Under these conditions, interactions between species are essential for supporting the growth of syntrophic species and maintaining thermodynamic feasibility of anaerobic fermentation. Kinetic models provide a simplified view of complex metabolic networks, while genome-scale metabolic models and flux-balance analysis (FBA) aim to unravel these systems as a whole. The target of this review is to outline the main similarities, differences and challenges associated with kinetic and metabolic modelling, and describe state-of-the-art modelling practices for studying syntrophies in the anaerobic digestion (AD) case study.

Identifiants

pubmed: 37542746
pii: S1369-5274(23)00100-5
doi: 10.1016/j.mib.2023.102363
pii:
doi:

Types de publication

Journal Article Review Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

102363

Informations de copyright

Copyright © 2023 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Arianna Basile (A)

Medical Research Council Toxicology Unit, University of Cambridge, Cambridge, UK. Electronic address: ab2851@mrc-tox.cam.ac.uk.

Guido Zampieri (G)

Department of Biology, University of Padova, Via U. Bassi 58/b, 35121 Padova, Italy.

Adam Kovalovszki (A)

Department of Environmental and Resource Engineering, Technical University of Denmark, Building 115, Bygningstorvet, 2800 Kgs. Lyngby, Denmark.

Behzad Karkaria (B)

Medical Research Council Toxicology Unit, University of Cambridge, Cambridge, UK.

Laura Treu (L)

Department of Biology, University of Padova, Via U. Bassi 58/b, 35121 Padova, Italy. Electronic address: laura.treu@unipd.it.

Kiran Raosaheb Patil (KR)

Medical Research Council Toxicology Unit, University of Cambridge, Cambridge, UK.

Stefano Campanaro (S)

Department of Biology, University of Padova, Via U. Bassi 58/b, 35121 Padova, Italy.

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Classifications MeSH