Amorphous Calcium Phosphate and Amorphous Calcium Phosphate Carboxylate: Synthesis and Characterization.
Journal
ACS omega
ISSN: 2470-1343
Titre abrégé: ACS Omega
Pays: United States
ID NLM: 101691658
Informations de publication
Date de publication:
01 Aug 2023
01 Aug 2023
Historique:
received:
07
02
2023
accepted:
27
06
2023
medline:
7
8
2023
pubmed:
7
8
2023
entrez:
7
8
2023
Statut:
epublish
Résumé
Amorphous calcium phosphate (ACP) is the first solid phase precipitated from a supersaturated calcium phosphate solution. Naturally, ACP is formed during the initial stages of biomineralization and stabilized by an organic compound. Carboxylic groups containing organic compounds are known to regulate the nucleation and crystallization of hydroxyapatite. Therefore, from a biomimetic point of view, the synthesis of carboxylate ions containing ACP (ACPC) is valuable. Usually, ACP is synthesized with fewer steps than ACPC. The precipitation reaction of ACP is rapid and influenced by pH, temperature, precursor concentration, stirring conditions, and reaction time. Due to phosphates triprotic nature, controlling pH in a multistep approach becomes tedious. Here, we developed a new ACP and ACPC synthesis approach and thoroughly characterized the obtained materials. Results from vibration spectroscopy, nuclear magnetic resonance (NMR), X-ray photoelectron spectroscopy (XPS), true density, specific surface area, and ion release studies have shown a difference in the physiochemical properties of the ACP and ACPC. Additionally, the effect of a carboxylic ion type on the physiochemical properties of ACPC was characterized. All of the ACPs and ACPCs were synthesized in sterile conditions, and in vitro analysis was performed using MC-3T3E1 cells, revealing the cytocompatibility of the synthesized ACPs and ACPCs, of which the ACPC synthesized with citrate showed the highest cell viability.
Identifiants
pubmed: 37546623
doi: 10.1021/acsomega.3c00796
pmc: PMC10399191
doi:
Types de publication
Journal Article
Langues
eng
Pagination
26782-26792Informations de copyright
© 2023 The Authors. Published by American Chemical Society.
Déclaration de conflit d'intérêts
The authors declare no competing financial interest.
Références
J Regen Med Tissue Eng. 2014;3:4
pubmed: 25745562
J Biomater Appl. 2019 Aug;34(2):273-283
pubmed: 31046511
Acta Biomater. 2010 Sep;6(9):3362-78
pubmed: 20167295
Nat Commun. 2020 Jan 3;11(1):102
pubmed: 31900386
Mater Sci Eng C Mater Biol Appl. 2017 Jan 1;70(Pt 2):1120-1124
pubmed: 27772712
Langmuir. 2013 Sep 17;29(37):11681-6
pubmed: 24007413
Nat Mater. 2010 Dec;9(12):1010-4
pubmed: 21076415
ACS Biomater Sci Eng. 2021 Jun 14;7(6):2346-2357
pubmed: 33973778
Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):E1354-63
pubmed: 24706850
Madridge J Dent Oral Surg. 2018;3(1):85-90
pubmed: 30906931
Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):4152-4157
pubmed: 29610354
Sci Rep. 2017 Mar 31;7:45655
pubmed: 28361908
Polymers (Basel). 2018 Oct 18;10(10):
pubmed: 30961090
Materials (Basel). 2018 Jan 26;11(2):
pubmed: 29373487
J Colloid Interface Sci. 2003 Dec 1;268(1):37-42
pubmed: 14611769
J Dent Res. 1997 Aug;76(8):1433-6
pubmed: 9240379
J Adv Res. 2018 May 24;14:53-62
pubmed: 30023133
Sci Rep. 2018 Nov 19;8(1):17016
pubmed: 30451901
Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22425-9
pubmed: 21127269
J Radioanal Nucl Chem. 2014;299(3):2027-2036
pubmed: 26224967
Sci Technol Adv Mater. 2022 Jul 20;23(1):434-445
pubmed: 35875328
ACS Omega. 2020 Oct 16;5(42):27204-27210
pubmed: 33134681
Bone. 2018 Sep;114:189-197
pubmed: 29929041
Sci Rep. 2021 Apr 5;11(1):7512
pubmed: 33820932
Monogr Oral Sci. 2001;18:77-93
pubmed: 11758449
Nutrients. 2019 Oct 25;11(11):
pubmed: 31731473
Phys Chem Chem Phys. 2016 Jul 27;18(30):20330-7
pubmed: 27276013
Biochem J. 1970 Sep;119(2):129-38
pubmed: 4922961
Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22369-70
pubmed: 21169505
Front Bioeng Biotechnol. 2023 Apr 05;11:1150037
pubmed: 37091348
Bioact Mater. 2021 Jan 26;6(8):2360-2371
pubmed: 33553821
Nat Commun. 2022 Mar 21;13(1):1496
pubmed: 35314701
Nat Commun. 2018 Oct 9;9(1):4170
pubmed: 30302020
Metallomics. 2018 Jun 20;10(6):802-817
pubmed: 29808889
Open Bone J. 2012;4:
pubmed: 24194797
ACS Appl Mater Interfaces. 2016 Oct 19;8(41):28116-28123
pubmed: 27593160
Chem Rev. 2008 Nov;108(11):4628-69
pubmed: 18816145
J Mater Chem B. 2021 Jun 23;9(24):4832-4845
pubmed: 33998626