Native top-down proteomics reveals EGFR-ERα signaling crosstalk in breast cancer cells dissociates NUTF2 dimers to modulate ERα signaling and cell growth.
Journal
Research square
Titre abrégé: Res Sq
Pays: United States
ID NLM: 101768035
Informations de publication
Date de publication:
24 Jul 2023
24 Jul 2023
Historique:
pubmed:
7
8
2023
medline:
7
8
2023
entrez:
7
8
2023
Statut:
epublish
Résumé
Oligomerization of proteins and their modified forms (proteoforms) produces functional protein complexes
Identifiants
pubmed: 37546719
doi: 10.21203/rs.3.rs-3097806/v1
pmc: PMC10402242
pii:
doi:
Types de publication
Preprint
Langues
eng
Subventions
Organisme : NHLBI NIH HHS
ID : R01 HL165168
Pays : United States
Organisme : NIGMS NIH HHS
ID : R44 GM130262
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG077046
Pays : United States
Organisme : NIGMS NIH HHS
ID : P41 GM108569
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA275142
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG075862
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA220284
Pays : United States
Déclaration de conflit d'intérêts
Competing Interests: KRD and NLK are involved in the commercialization of top-down proteomics software including ProSight Native. The other authors have no competing interests to disclose.