Region-specific reversal of epidermal planar polarity in the fancy

The planar cell polarity (PCP) pathway collectively orients thousands of cells with respect to a body axis to direct cellular behaviors that are essential for embryonic morphogenesis. Hair follicles of the murine epidermis provide a striking readout of PCP activity in their uniform alignment along the entire skin surface. Here, we characterize, from the molecular to tissue-scale, PCP establishment in the Region-specific rotation of the Planar Cell Polarity axis reverses posterior hair follicles in the fancy