Chronic Limb-Threatening Ischemia in Patients with Type 2 Diabetes: Revascularization Index as a Predictor for Primary Endovascular Intervention Outcome.


Journal

Vascular health and risk management
ISSN: 1178-2048
Titre abrégé: Vasc Health Risk Manag
Pays: New Zealand
ID NLM: 101273479

Informations de publication

Date de publication:
2023
Historique:
received: 04 11 2022
accepted: 21 06 2023
medline: 8 8 2023
pubmed: 7 8 2023
entrez: 7 8 2023
Statut: epublish

Résumé

Chronic limb-threatening ischemia in patients with diabetes is associated with a high risk of adverse outcomes. The associated co-morbidities, the heterogeneity of foot presentation and the distribution of atherosclerotic lesions led to the emergence of multiple revascularization strategies and scoring systems to improve management outcomes. This study aimed to introduce a new index, the revascularization index (RI), and to assess its predictive value for the outcomes of primary endovascular intervention in patients with type 2 diabetes presenting with chronic limb-threatening ischemia. A retrospective electronic medical records review was conducted for patients with type 2 diabetes presenting with chronic limb-threatening ischemia managed at King Abdullah University Hospital by primary endovascular interventions between January 2014 and August 2019. The RI was analyzed for its predictive value for the treatment outcomes. A total of 187 patients were included in this study, with a major lower limb amputation rate of 19.3%. The performance of the RI was excellent in predicting secondary revascularization (AUC = 0.80, 95% CI: 0.73-0.86, The RI can be used to predict major adverse lower limb events (MALE). It might be used as a guide for the extent of endovascular interventions for diabetic chronic limb-threatening ischemia with multi-level outflow atherosclerotic disease.

Identifiants

pubmed: 37547281
doi: 10.2147/VHRM.S394521
pii: 394521
pmc: PMC10402884
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

495-504

Informations de copyright

© 2023 Shatnawi et al.

Déclaration de conflit d'intérêts

The authors report no conflicts of interest in this work.

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Auteurs

Nawaf J Shatnawi (NJ)

Department of Surgery, Jordan University of Science and Technology, Irbid, Jordan.

Nabil A Al-Zoubi (NA)

Department of Surgery, Jordan University of Science and Technology, Irbid, Jordan.

Lujain A Al-Bakkar (LA)

Department of Surgery, Jordan University of Science and Technology, Irbid, Jordan.

Ammar M Abu-Baker (AM)

Department of Surgery, Jordan University of Science and Technology, Irbid, Jordan.

Yousef S Khader (YS)

Department of Community Medicine, Public Health and Family Medicine, Jordan University of Science and Technology, Irbid, Jordan.

Mamoon Al-Omari (M)

Department of Radiology, Jordan University of Science and Technology, Irbid, Jordan.

Mowafeq A El-Heis (MA)

Department of Radiology, Jordan University of Science and Technology, Irbid, Jordan.

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