Clinical efficacy of probiotics in prevention of infectious diseases among hospitalized patients in ICU and non-ICU wards in clinical randomized trials: A systematic review.

Clostridioides difficile infection antibiotic‐associated diarrhea nosocomial infections probiotic ventilator‐associated pneumonia

Journal

Health science reports
ISSN: 2398-8835
Titre abrégé: Health Sci Rep
Pays: United States
ID NLM: 101728855

Informations de publication

Date de publication:
Aug 2023
Historique:
received: 07 04 2023
revised: 13 07 2023
accepted: 18 07 2023
medline: 7 8 2023
pubmed: 7 8 2023
entrez: 7 8 2023
Statut: epublish

Résumé

The present study aimed to review probiotics' clinical efficacy in preventing infectious diseases among hospitalized patients in ICU and non-ICU wards. A search of Medline, EMBASE, The Cochrane Library, Science Direct, Open Grey, and Google Scholar was conducted for eligible publications from 2002 to 2020 following the requirements outlined in the PRISMA guideline. The search strategy was based on the combination of the following terms: "probiotics," "prebiotics," "synbiotics," and "cross-infection." The logical operators "AND" (or the equivalent operator for the databases) and "OR" (e.g., probiotics OR prebiotics OR synbiotics) were used. The results indicated that the probiotic consumption caused a significant reduction in antibiotic-associated diarrhea (AAD) and This systematic review shows that the administration of probiotics has moderate preventive or mitigating effects on the occurrence of VAP in ICU patients, CDI, AAD, and nosocomial infections among children. Consequently, applying antibiotics along with the proper probiotic species can be advantageous.

Sections du résumé

Background and Aims UNASSIGNED
The present study aimed to review probiotics' clinical efficacy in preventing infectious diseases among hospitalized patients in ICU and non-ICU wards.
Methods UNASSIGNED
A search of Medline, EMBASE, The Cochrane Library, Science Direct, Open Grey, and Google Scholar was conducted for eligible publications from 2002 to 2020 following the requirements outlined in the PRISMA guideline. The search strategy was based on the combination of the following terms: "probiotics," "prebiotics," "synbiotics," and "cross-infection." The logical operators "AND" (or the equivalent operator for the databases) and "OR" (e.g., probiotics OR prebiotics OR synbiotics) were used.
Results UNASSIGNED
The results indicated that the probiotic consumption caused a significant reduction in antibiotic-associated diarrhea (AAD) and
Conclusion UNASSIGNED
This systematic review shows that the administration of probiotics has moderate preventive or mitigating effects on the occurrence of VAP in ICU patients, CDI, AAD, and nosocomial infections among children. Consequently, applying antibiotics along with the proper probiotic species can be advantageous.

Identifiants

pubmed: 37547361
doi: 10.1002/hsr2.1469
pii: HSR21469
pmc: PMC10400784
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e1469

Informations de copyright

© 2023 The Authors. Health Science Reports published by Wiley Periodicals LLC.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

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Auteurs

Atieh Darbandi (A)

Molecular Microbiology Research Center Shahed University Tehran Iran.

Maryam Banar (M)

Department of Pathobiology School of Public Health, Tehran University of Medical Sciences Tehran Iran.

Maryam Koupaei (M)

Department of Microbiology and Immunology School of Medicine, Kashan University of Medical Sciences Kashan Iran.

Roghayeh Afifirad (R)

Department of Microbiology School of Medicine, Tehran University of Medical Sciences Tehran Iran.

Parisa Asadollahi (P)

Department of Microbiology Faculty of Medicine, Ilam University of Medical Sciences Ilam Iran.

Elnaz Bafandeh (E)

Department of Medical Biotechnology Faculty of Medicine, Lorestan University of Medical Sciences Khorramabad Iran.

Iraj Rasooli (I)

Molecular Microbiology Research Center, Faculty of Sciences Shahed University Tehran Iran.

Amir Emamie (A)

Department of Pathobiology School of Public Health, Tehran University of Medical Sciences Tehran Iran.

Tahereh Navidifar (T)

Shoushtar Faculty of Medical Sciences Shoushtar Iran.

Parviz Owlia (P)

Molecular Microbiology Research Center Shahed University Tehran Iran.
Molecular Microbiology Research Center, Faculty of Sciences Shahed University Tehran Iran.

Classifications MeSH