Characteristics of multiple sclerosis and demyelinating disease in an Asian American population.
Asian
Indian
MS
NMOSD
ancestry
race
Journal
Multiple sclerosis (Houndmills, Basingstoke, England)
ISSN: 1477-0970
Titre abrégé: Mult Scler
Pays: England
ID NLM: 9509185
Informations de publication
Date de publication:
09 2023
09 2023
Historique:
medline:
15
9
2023
pubmed:
7
8
2023
entrez:
7
8
2023
Statut:
ppublish
Résumé
Race and ancestry influence the course of multiple sclerosis (MS). Explore clinical characteristics of MS and neuromyelitis optica spectrum disorder (NMOSD) in Asian American patients. Chart review was performed for 282 adults with demyelinating disease who self-identified as Asian at a single North American MS center. Demographics and clinical characteristics were compared to non-Asian MS patients and by region of Asian ancestry. Region of ancestry was known for 181 patients. Most (94.7%) preferred English, but fewer East Asian patients did (80%, MS severity was similar between Asian American patients and non-Asian patients. Region of ancestry was associated with differences in sociodemographics and MS severity. Further research is needed to uncover genetic, socioeconomic, or environmental factors causing these differences.
Sections du résumé
BACKGROUND
Race and ancestry influence the course of multiple sclerosis (MS).
OBJECTIVES
Explore clinical characteristics of MS and neuromyelitis optica spectrum disorder (NMOSD) in Asian American patients.
METHODS
Chart review was performed for 282 adults with demyelinating disease who self-identified as Asian at a single North American MS center. Demographics and clinical characteristics were compared to non-Asian MS patients and by region of Asian ancestry.
RESULTS
Region of ancestry was known for 181 patients. Most (94.7%) preferred English, but fewer East Asian patients did (80%,
CONCLUSIONS
MS severity was similar between Asian American patients and non-Asian patients. Region of ancestry was associated with differences in sociodemographics and MS severity. Further research is needed to uncover genetic, socioeconomic, or environmental factors causing these differences.
Identifiants
pubmed: 37548214
doi: 10.1177/13524585231188486
doi:
Substances chimiques
Aquaporin 4
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM