Telomere Shortening of Barrett's Esophagus and Esophageal Adenocarcinoma in Japanese Patients.

Barrett’s esophagus Japanese Telomere esophageal adenocarcinoma long-segment Barrett’s esophagus real-time PCR short-segment Barrett’s esophagus

Journal

Cancer investigation
ISSN: 1532-4192
Titre abrégé: Cancer Invest
Pays: England
ID NLM: 8307154

Informations de publication

Date de publication:
Sep 2023
Historique:
medline: 7 9 2023
pubmed: 7 8 2023
entrez: 7 8 2023
Statut: ppublish

Résumé

Telomere shortening is deeply involved in many types of cancer. Telomere length of esophageal adenocarcinoma (EAC) and Barrett's esophagus (BE) was examined in Japanese patients. Among BE from cancer free patients (Cancer free), BE from patients with EAC (Adjacent) and EAC tissue (Cancer), Cancer free group presented the longest telomeres, while Cancer group presented the shortest telomeres and Adjacent group presented intermediate telomeres. Direction of endoscopic biopsy, 2 o'clock direction was also significantly associated with shorter telomere length in non-neoplastic BE (

Identifiants

pubmed: 37548421
doi: 10.1080/07357907.2023.2245897
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

640-645

Auteurs

Tomomitsu Tahara (T)

Third department of internal medicine, Kansai Medical University, Hirakata, Japan.

Takuya Shijimaya (T)

Third department of internal medicine, Kansai Medical University, Hirakata, Japan.

Jumpei Yamazaki (J)

Translational Research Unit, Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
One Health Research Center, Hokkaido University, Sapporo, Japan.

Takashi Tomiyama (T)

Third department of internal medicine, Kansai Medical University, Hirakata, Japan.

Toshiro Fukui (T)

Third department of internal medicine, Kansai Medical University, Hirakata, Japan.

Makoto Naganuma (M)

Third department of internal medicine, Kansai Medical University, Hirakata, Japan.

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Classifications MeSH