Analysis of the efficacy of a single subumbilical stoma for bilateral cutaneous ureterostomy after radical cystectomy.


Journal

European journal of medical research
ISSN: 2047-783X
Titre abrégé: Eur J Med Res
Pays: England
ID NLM: 9517857

Informations de publication

Date de publication:
07 Aug 2023
Historique:
received: 10 11 2022
accepted: 27 07 2023
medline: 9 8 2023
pubmed: 8 8 2023
entrez: 7 8 2023
Statut: epublish

Résumé

Radical cystectomy and urinary diversion are the standard surgical treatments for patients with muscle-invasive or high-risk, or recurrent non-muscle-invasive bladder cancer. Although this approach significantly prolongs patient survival, it can lead to postoperative complications. This study aims to compare the efficacy and complications of bilateral cutaneous ureterostomy with a single subumbilical stoma to those of cutaneous ureterostomy with two stomas and an ileal conduit as a means of urinary diversion after radical cystectomy. The findings of this study will provide valuable information for healthcare providers in selecting the appropriate urinary diversion method for their patients. The clinical data for 108 patients who received bilateral cutaneous ureterostomy with a single subumbilical stoma (ureterostomy with a single stoma group), cutaneous ureterostomy with two stomas (ureterostomy with two stomas group), or an ileal conduit (ileal conduit group) after radical cystectomy were retrospectively analysed. The operative time, pathological stage, survival status, perioperative complication rate, rate of successful first extubation, rehospitalization rate at 6 months after surgery,ostomy-related medical costs,and postoperative quality of life were compared between the three groups of patients. A significant difference in the operative time was found between the three groups (P = 0.001). No significant differences in pathological stage, survival status, perioperative complication rate, rehospitalization rate at 6 months after surgery, or bladder cancer index (BCI) score were identified among the three groups. The difference in the successful first extubation rate between the three groups of patients was significant (P = 0.001). Significant differences in ostomy-related medical costs were observed among the three groups of patients (P = 0.006). A single subumbilical stoma for bilateral cutaneous ureterostomy after radical cystectomy may result in shorter surgery time, increased success rates for initial catheter removal, and lower medical expenses. However, to confirm these findings, further prospective randomized clinical trials are necessary.

Sections du résumé

BACKGROUND BACKGROUND
Radical cystectomy and urinary diversion are the standard surgical treatments for patients with muscle-invasive or high-risk, or recurrent non-muscle-invasive bladder cancer. Although this approach significantly prolongs patient survival, it can lead to postoperative complications. This study aims to compare the efficacy and complications of bilateral cutaneous ureterostomy with a single subumbilical stoma to those of cutaneous ureterostomy with two stomas and an ileal conduit as a means of urinary diversion after radical cystectomy. The findings of this study will provide valuable information for healthcare providers in selecting the appropriate urinary diversion method for their patients.
METHODS METHODS
The clinical data for 108 patients who received bilateral cutaneous ureterostomy with a single subumbilical stoma (ureterostomy with a single stoma group), cutaneous ureterostomy with two stomas (ureterostomy with two stomas group), or an ileal conduit (ileal conduit group) after radical cystectomy were retrospectively analysed. The operative time, pathological stage, survival status, perioperative complication rate, rate of successful first extubation, rehospitalization rate at 6 months after surgery,ostomy-related medical costs,and postoperative quality of life were compared between the three groups of patients.
RESULTS RESULTS
A significant difference in the operative time was found between the three groups (P = 0.001). No significant differences in pathological stage, survival status, perioperative complication rate, rehospitalization rate at 6 months after surgery, or bladder cancer index (BCI) score were identified among the three groups. The difference in the successful first extubation rate between the three groups of patients was significant (P = 0.001). Significant differences in ostomy-related medical costs were observed among the three groups of patients (P = 0.006).
CONCLUSION CONCLUSIONS
A single subumbilical stoma for bilateral cutaneous ureterostomy after radical cystectomy may result in shorter surgery time, increased success rates for initial catheter removal, and lower medical expenses. However, to confirm these findings, further prospective randomized clinical trials are necessary.

Identifiants

pubmed: 37550747
doi: 10.1186/s40001-023-01250-z
pii: 10.1186/s40001-023-01250-z
pmc: PMC10405402
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

273

Subventions

Organisme : Key Research and Development Program of Jiangsu Province under Grant Agreement
ID : BE2020654

Informations de copyright

© 2023. BioMed Central Ltd., part of Springer Nature.

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Auteurs

Zhenyu Fu (Z)

Department of Urology, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
Department of Urology, Changshu No. 2 People's Hospital, Changshu, Jiangsu, China.

Zhen Tian (Z)

Department of Urology, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.

Yongchang Chen (Y)

Department of Urology, Changshu No. 2 People's Hospital, Changshu, Jiangsu, China.

Zongming Jia (Z)

Department of Urology, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.

Chengyu Wang (C)

Department of Urology, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.

Xuefeng Zhang (X)

Department of Urology, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.

Weijie Zhang (W)

Department of Urology, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.

Gang Li (G)

Department of Urology, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.

Xuedong Wei (X)

Department of Urology, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China. wxd0422@163.com.

Yuhua Huang (Y)

Department of Urology, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China. sdfyy_hyh@163.com.

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Classifications MeSH