Polymorphism of LRP4 Gene (rs9667108) among Post Menopause Women with Osteoporosis.
Osteoporosis
PCR
Polymorphism genetics
Single nucleotide polymorphisms (SNPs)
Journal
Iranian journal of public health
ISSN: 2251-6093
Titre abrégé: Iran J Public Health
Pays: Iran
ID NLM: 7505531
Informations de publication
Date de publication:
Apr 2023
Apr 2023
Historique:
received:
19
08
2021
accepted:
20
11
2021
medline:
8
8
2023
pubmed:
8
8
2023
entrez:
8
8
2023
Statut:
ppublish
Résumé
Many studies have been done to identify the factors that influence the development and progression of osteoporosis. One genetic factor is polymorphisms of This case-control study has been conducted at GhaemShahr Valiasr Hospital on 100 female patients with osteoporosis (average age of 58.1) and 90 healthy females without osteoporosis (average age of 55.2). After sampling and extraction of genomic DNA via of the salt deposition method, the genotype and SNP (rs9667108) polymorphism of The statistical analysis has shown the significant relationship between SNP (rs9667108) polymorphism and the risk of osteoporosis disease in patients and control groups ( The existence of mutation in the
Sections du résumé
Background
UNASSIGNED
Many studies have been done to identify the factors that influence the development and progression of osteoporosis. One genetic factor is polymorphisms of
Methods
UNASSIGNED
This case-control study has been conducted at GhaemShahr Valiasr Hospital on 100 female patients with osteoporosis (average age of 58.1) and 90 healthy females without osteoporosis (average age of 55.2). After sampling and extraction of genomic DNA via of the salt deposition method, the genotype and SNP (rs9667108) polymorphism of
Results
UNASSIGNED
The statistical analysis has shown the significant relationship between SNP (rs9667108) polymorphism and the risk of osteoporosis disease in patients and control groups (
Conclusion
UNASSIGNED
The existence of mutation in the
Identifiants
pubmed: 37551184
doi: 10.18502/ijph.v52i4.12457
pii: IJPH-52-840
pmc: PMC10404332
doi:
Types de publication
Journal Article
Langues
eng
Pagination
840-847Informations de copyright
Copyright © 2023 Kavoosian et al. Published by Tehran University of Medical Sciences.
Déclaration de conflit d'intérêts
Conflict of Interest The authors declare that there is no conflict of interests.
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