Severe COVID-19 classified by simple covid risk index is associated with higher levels of advanced oxidation protein products and 8-hydroxy 2 deoxyguanosine.
8-OHDG
AOPP
COVID-19
SCRI
oxidative stress
Journal
Epidemiology and infection
ISSN: 1469-4409
Titre abrégé: Epidemiol Infect
Pays: England
ID NLM: 8703737
Informations de publication
Date de publication:
09 08 2023
09 08 2023
Historique:
medline:
5
9
2023
pubmed:
9
8
2023
entrez:
9
8
2023
Statut:
epublish
Résumé
SARS-CoV-2 has become one of the most important and challenging medical research topics in recent years. The presence of endothelial dysfunction, immune thrombosis, and oxidative stress contributes to complications and requires more extended hospitalisation of patients. In this article, we focused on analysing the impact of oxidative stress on the severity of COVID-19 infection. The study group consisted of 72 patients with laboratory-confirmed SARS-CoV enrolled. The patients were divided into moderate and severe diseases according to the SCRI (Simple Covid Risk Index, including lymphocyte/D-dimer ratio). Using the ELISA kit, we determined the level of AOPP and 8-OHdG. Patients with severe COVID-19 had higher levels of both AOPP (
Identifiants
pubmed: 37554121
doi: 10.1017/S0950268823001280
pii: S0950268823001280
pmc: PMC10540163
doi:
Substances chimiques
8-Hydroxy-2'-Deoxyguanosine
88847-89-6
Advanced Oxidation Protein Products
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e140Références
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