Outcomes of aortic valve repair with the reimplantation technique and maintenance of commissural orientation.

Reimplantation aortic root aortic valve repair bicuspid aortic valve (BAV) valve-sparing

Journal

Annals of cardiothoracic surgery
ISSN: 2225-319X
Titre abrégé: Ann Cardiothorac Surg
Pays: China
ID NLM: 101605877

Informations de publication

Date de publication:
31 Jul 2023
Historique:
received: 05 05 2023
accepted: 19 06 2023
medline: 9 8 2023
pubmed: 9 8 2023
entrez: 9 8 2023
Statut: ppublish

Résumé

Debate still persists on whether valve-sparing root reimplantation (VSRR) of a very asymmetric bicuspid aortic valve (BAV) should be completed such that the asymmetry of the native commissural orientation is retained, or if it should be made symmetric (180°-180°). Herein, we present our approach, in which the native asymmetry is preserved, and the valve is reimplanted in a 210°-150° orientation. A retrospective review was performed of 130 patients with BAV who underwent VSRR between January 1, 2004 and March 1, 2023 at a single institution. Of this total, 37 were reimplanted asymmetrically (210°-150°). The primary outcome was > moderate aortic insufficiency (AI). Secondary outcomes included severe aortic stenosis (AS), reintervention, and survival. The included 37 patients were mostly male [94.6% (35/37)] with mean age of 46.3 years, and with low rates of comorbidities. At least moderate AI was present in 40.5% (15/37) prior to surgery. All BAV in this series were Sievers Type 1 with a mean commissural angle of 128.2°. Leaflet repair was required in 81.1% (30/37), most commonly involving central plication of the conjoined cusp [96.7% (29/30)] and raphe release [73.3% (22/30)]. There was no 30-day mortality or stroke. At 10 years, the cumulative incidences of > moderate AI, severe AS, and reintervention were 7.6% (0-17.2%), 7.1% (0-19.7%), and 5.3% (0.3-22%), respectively. There was no mortality for the entire duration of the study period. This series demonstrates excellent 10-year outcomes of maintaining commissural orientation in asymmetric BAV reimplantation procedures. However, further study with additional patients, longer follow-up, and direct comparison to symmetric reimplantation for similar BAV morphology is required.

Sections du résumé

Background UNASSIGNED
Debate still persists on whether valve-sparing root reimplantation (VSRR) of a very asymmetric bicuspid aortic valve (BAV) should be completed such that the asymmetry of the native commissural orientation is retained, or if it should be made symmetric (180°-180°). Herein, we present our approach, in which the native asymmetry is preserved, and the valve is reimplanted in a 210°-150° orientation.
Methods UNASSIGNED
A retrospective review was performed of 130 patients with BAV who underwent VSRR between January 1, 2004 and March 1, 2023 at a single institution. Of this total, 37 were reimplanted asymmetrically (210°-150°). The primary outcome was > moderate aortic insufficiency (AI). Secondary outcomes included severe aortic stenosis (AS), reintervention, and survival.
Results UNASSIGNED
The included 37 patients were mostly male [94.6% (35/37)] with mean age of 46.3 years, and with low rates of comorbidities. At least moderate AI was present in 40.5% (15/37) prior to surgery. All BAV in this series were Sievers Type 1 with a mean commissural angle of 128.2°. Leaflet repair was required in 81.1% (30/37), most commonly involving central plication of the conjoined cusp [96.7% (29/30)] and raphe release [73.3% (22/30)]. There was no 30-day mortality or stroke. At 10 years, the cumulative incidences of > moderate AI, severe AS, and reintervention were 7.6% (0-17.2%), 7.1% (0-19.7%), and 5.3% (0.3-22%), respectively. There was no mortality for the entire duration of the study period.
Conclusions UNASSIGNED
This series demonstrates excellent 10-year outcomes of maintaining commissural orientation in asymmetric BAV reimplantation procedures. However, further study with additional patients, longer follow-up, and direct comparison to symmetric reimplantation for similar BAV morphology is required.

Identifiants

pubmed: 37554706
doi: 10.21037/acs-2023-avs2-18
pii: acs-12-04-318
pmc: PMC10405331
doi:

Types de publication

Journal Article

Langues

eng

Pagination

318-325

Informations de copyright

2023 Annals of Cardiothoracic Surgery. All rights reserved.

Déclaration de conflit d'intérêts

Conflicts of Interest: The authors have no conflicts of interest to declare.

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Auteurs

John J Kelly (JJ)

Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

Nimesh D Desai (ND)

Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

William L Patrick (WL)

Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

Brittany J Cannon (BJ)

Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

Yu Zhao (Y)

Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

Selim Mosbahi (S)

Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

Mikolaj Berezowksi (M)

Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

Amit Iyengar (A)

Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

Wilson Y Szeto (WY)

Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

Joseph E Bavaria (JE)

Division of Cardiovascular Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.

Classifications MeSH