The effect of cocaine on patients undergoing total hip arthroplasty.
Cocaine
Cost of care
Length of stay
Total hip arthroplasty
Journal
Journal of orthopaedics
ISSN: 0972-978X
Titre abrégé: J Orthop
Pays: India
ID NLM: 101233220
Informations de publication
Date de publication:
Sep 2023
Sep 2023
Historique:
received:
08
06
2023
revised:
24
07
2023
accepted:
25
07
2023
pmc-release:
01
09
2024
medline:
9
8
2023
pubmed:
9
8
2023
entrez:
9
8
2023
Statut:
epublish
Résumé
Cocaine use has surged in the past decade, with 4.8 million Americans (1.7% of the population greater than 12) reporting use in 2021, leading to a healthcare burden of 1.3 billion dollars. Cocaine users experience prolonged hospital stays, higher costs, worse surgical outcomes, increased risk of medical conditions, and inflammation-related osteoarthritis. The study aims to identify factors influencing length of stay, costs, and perioperative complications in cocaine users undergoing total hip arthroplasty (THA) to reduce these risks. This study utilized the NIS database, providing comprehensive information on patient demographics, length of stay, hospital costs, and complications. Statistical analyses were conducted using SPSS software, including propensity matching and significance testing, to compare outcomes between cocaine users (CU) and non-cocaine users (NCU) undergoing total hip arthroplasty. After propensity matching, cocaine users had a significantly longer LOS (4.8 days) in comparison to non-cocaine users (2.6 days) (p < 0.001). Similarly, the CU group had a larger of care (87984.9) than the NCU group (69149.2) (p < 0.001). Cocaine users had significantly higher rates of blood loss anemia (OR: 3.24, 95% CI: 2.21, 4.73), blood loss anemia (OR: 1.59, 95% CI: 1.12, 2.24), blood transfusion (OR: 2.23, 95% CI: 1.04, 4.78), periprosthetic dislocation (OR: 6.57, 95% CI: 1.47, 29.32), and periprosthetic infection (OR: 4.59, 95% CI: 1.54, 13.68) than patients in the non-cocaine user's group. Cocaine users had a significantly longer length of stay, higher costs of care, and an increased number of post-operative complications compared to non-cocaine users. These data contribute to understanding the potential ramifications of cocaine users undergoing THA.
Sections du résumé
Background
UNASSIGNED
Cocaine use has surged in the past decade, with 4.8 million Americans (1.7% of the population greater than 12) reporting use in 2021, leading to a healthcare burden of 1.3 billion dollars. Cocaine users experience prolonged hospital stays, higher costs, worse surgical outcomes, increased risk of medical conditions, and inflammation-related osteoarthritis. The study aims to identify factors influencing length of stay, costs, and perioperative complications in cocaine users undergoing total hip arthroplasty (THA) to reduce these risks.
Methods
UNASSIGNED
This study utilized the NIS database, providing comprehensive information on patient demographics, length of stay, hospital costs, and complications. Statistical analyses were conducted using SPSS software, including propensity matching and significance testing, to compare outcomes between cocaine users (CU) and non-cocaine users (NCU) undergoing total hip arthroplasty.
Results
UNASSIGNED
After propensity matching, cocaine users had a significantly longer LOS (4.8 days) in comparison to non-cocaine users (2.6 days) (p < 0.001). Similarly, the CU group had a larger of care (87984.9) than the NCU group (69149.2) (p < 0.001). Cocaine users had significantly higher rates of blood loss anemia (OR: 3.24, 95% CI: 2.21, 4.73), blood loss anemia (OR: 1.59, 95% CI: 1.12, 2.24), blood transfusion (OR: 2.23, 95% CI: 1.04, 4.78), periprosthetic dislocation (OR: 6.57, 95% CI: 1.47, 29.32), and periprosthetic infection (OR: 4.59, 95% CI: 1.54, 13.68) than patients in the non-cocaine user's group.
Conclusion
UNASSIGNED
Cocaine users had a significantly longer length of stay, higher costs of care, and an increased number of post-operative complications compared to non-cocaine users. These data contribute to understanding the potential ramifications of cocaine users undergoing THA.
Identifiants
pubmed: 37555205
doi: 10.1016/j.jor.2023.07.029
pii: S0972-978X(23)00176-9
pmc: PMC10404604
doi:
Types de publication
Journal Article
Langues
eng
Pagination
64-68Informations de copyright
© 2023 Published by Elsevier B.V. on behalf of Professor P K Surendran Memorial Education Foundation.
Déclaration de conflit d'intérêts
None.
Références
Clin Kidney J. 2014 Dec;7(6):513-7
pubmed: 25859366
Diabetes Res Clin Pract. 2007 Sep;77(3):485-8
pubmed: 17306411
WMJ. 2004;103(7):66-9
pubmed: 15696837
Arch Orthop Trauma Surg. 2018 Oct;138(10):1353-1358
pubmed: 29922852
Health Aff (Millwood). 2016 Jan;35(1):12-9
pubmed: 26733696
Cureus. 2022 Feb 10;14(2):e22090
pubmed: 35165645
Geriatr Orthop Surg Rehabil. 2023 May 22;14:21514593231178624
pubmed: 37250017
J Drug Educ. 1987;17(2):89-111
pubmed: 3612421
Curr Opin Psychiatry. 2013 Jul;26(4):349-54
pubmed: 23722099
Anesth Analg. 2021 Feb 1;132(2):305-307
pubmed: 33449554
Korean J Physiol Pharmacol. 2013 Aug;17(4):347-57
pubmed: 23946695
Open Orthop J. 2014 May 16;8:108-13
pubmed: 24894715
BMC Nephrol. 2019 Mar 20;20(1):99
pubmed: 30894132
Cureus. 2021 Nov 3;13(11):e19236
pubmed: 34877213
J Arthroplasty. 2017 Jun;32(6):1991-1995.e1
pubmed: 28161137
J Orthop. 2023 Apr 24;40:47-51
pubmed: 37188145
Proc Soc Exp Biol Med. 1994 Jan;205(1):29-34
pubmed: 8115348
J Knee Surg. 2018 Nov;31(10):928-933
pubmed: 30193389
Clin Orthop Relat Res. 2016 Feb;474(2):357-64
pubmed: 26040966
J Am Soc Nephrol. 2009 Apr;20(4):852-62
pubmed: 19211710
J Toxicol Clin Toxicol. 1990;28(3):321-30
pubmed: 2231831
Cureus. 2019 Dec 30;11(12):e6516
pubmed: 32025435
Transl Psychiatry. 2017 Feb 21;7(2):e1040
pubmed: 28221362
JAMA Netw Open. 2021 Mar 1;4(3):e210242
pubmed: 33666661
Subst Abuse Treat Prev Policy. 2020 Sep 29;15(1):73
pubmed: 32993719
BMC Nephrol. 2005 Sep 22;6:10
pubmed: 16176587
Clin Nephrol. 2009 Sep;72(3):234-6
pubmed: 19761732
Acta Orthop Scand. 2001 Apr;72(2):113-9
pubmed: 11372940
Hum Psychopharmacol. 2012 Mar;27(2):156-66
pubmed: 22389080
Bone Joint J. 2013 Nov;95-B(11 Suppl A):46-50
pubmed: 24187351
Hip Pelvis. 2018 Dec;30(4):197-201
pubmed: 30534537
J Pharmacol Exp Ther. 1994 Oct;271(1):311-8
pubmed: 7965730
Lancet. 2010 Aug 7;376(9739):419-30
pubmed: 20594588
Cell Tissue Res. 2009 Jun;336(3):385-92
pubmed: 19350275
Hand Surg. 2008;13(2):73-8
pubmed: 19054837
Cureus. 2020 Aug 19;12(8):e9865
pubmed: 32963906
Indian J Endocrinol Metab. 2012 Mar;16 Suppl 1:S27-36
pubmed: 22701840
Lancet. 2018 Nov 3;392(10158):1662-1671
pubmed: 30496081
Physiol Behav. 1993 Sep;54(3):509-13
pubmed: 8415945