Helminths revive to survive.
Journal
The Journal of experimental medicine
ISSN: 1540-9538
Titre abrégé: J Exp Med
Pays: United States
ID NLM: 2985109R
Informations de publication
Date de publication:
05 09 2022
05 09 2022
Historique:
medline:
11
8
2023
pubmed:
10
8
2023
entrez:
9
8
2023
Statut:
ppublish
Résumé
Helminth parasites are well known to have co-evolved a diverse arsenal of immunomodulatory factors to aid their persistence following infection. In this issue, Karo-Atar et al. (2022. J. Exp. Med.https://doi.org/10.1084/jem.20212311) demonstrate that products released by the gut-dwelling helminth Heligmosomoides polygyrus barkeri modify intestinal stem cells into a "revival" state, which is associated with a loss of helminth-expelling secretory cell types from the epithelium.
Identifiants
pubmed: 37559179
pii: 213395
doi: 10.1084/jem.20221183
pmc: PMC9375159
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Comment
Langues
eng
Sous-ensembles de citation
IM
Commentaires et corrections
Type : CommentOn
Informations de copyright
© 2022 Grainger and Daw.
Références
Sci Transl Med. 2010 Dec 1;2(60):60ra88
pubmed: 21123809
Trends Parasitol. 2020 Sep;36(9):761-772
pubmed: 32713764
J Exp Med. 2022 Jan 3;219(1):
pubmed: 34779829