Neuroprotective effects of idebenone on hydrogen peroxide-induced oxidative damage in retinal ganglion cells-5.
Apoptosis
Autophagy
Glaucomatous optic neuropathy
Idebenone
Oxidative stress
Journal
International ophthalmology
ISSN: 1573-2630
Titre abrégé: Int Ophthalmol
Pays: Netherlands
ID NLM: 7904294
Informations de publication
Date de publication:
Oct 2023
Oct 2023
Historique:
received:
30
11
2022
accepted:
27
07
2023
medline:
18
9
2023
pubmed:
10
8
2023
entrez:
10
8
2023
Statut:
ppublish
Résumé
To investigate the neuroprotective effect of idebenone against hydrogen peroxide (H RGC-5 cells were pre-treated with various idebenone concentrations (5, 10, and 20 µM) for 12 h and were then subjected to 300 µM H Flow cytometry showed that the apoptosis rates in the normal control group, H Idebenone protects RGC-5 cells against H
Identifiants
pubmed: 37561250
doi: 10.1007/s10792-023-02831-x
pii: 10.1007/s10792-023-02831-x
doi:
Substances chimiques
Neuroprotective Agents
0
idebenone
HB6PN45W4J
Hydrogen Peroxide
BBX060AN9V
Beclin-1
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
3831-3839Subventions
Organisme : the National Nature Science Foundation of China
ID : No.81470637
Organisme : the Natural Science Foundation of Xiamen
ID : 3502Z20227277
Informations de copyright
© 2023. The Author(s), under exclusive licence to Springer Nature B.V.
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