Overview of therapeutic drug monitoring and clinical practice.

Individualized drug delivery Monitoring tools Therapeutic drug monitoring Trending hotspots

Journal

Talanta
ISSN: 1873-3573
Titre abrégé: Talanta
Pays: Netherlands
ID NLM: 2984816R

Informations de publication

Date de publication:
01 Jan 2024
Historique:
received: 03 04 2023
revised: 29 06 2023
accepted: 25 07 2023
medline: 20 9 2023
pubmed: 11 8 2023
entrez: 10 8 2023
Statut: ppublish

Résumé

With the rapid development of clinical pharmacy in China, therapeutic drug monitoring (TDM) has become an essential tool for guiding rational clinical drug use and is widely concerned. TDM is a tool that combines pharmacokinetic and pharmacodynamic knowledge to optimize personalized drug therapy, which can improve treatment outcomes, reduce drug-drug toxicity, and avoid the risk of developing drug resistance. To effectively implement TDM, accurate and sophisticated analytical methods are required. By researching the literature published in recent years, we summarize the types of commonly monitored drugs, therapeutic windows, and clinical assays and track the trends and hot spots of therapeutic drug monitoring. The purpose is to provide guidelines for clinical blood drug concentration monitoring, to implement individualized drug delivery programs better, to ensure the rational use of drugs for patients, and to provide a reference for the group to carry out related topics in the future.

Identifiants

pubmed: 37562225
pii: S0039-9140(23)00747-6
doi: 10.1016/j.talanta.2023.124996
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

124996

Informations de copyright

Copyright © 2023 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Zijun Fang (Z)

University of Southwest Petroleum University, College of Mechanical and Electrical Engineering, Chengdu, China.

He Zhang (H)

University of Southwest Petroleum University, College of Mechanical and Electrical Engineering, Chengdu, China.

Jiuchuan Guo (J)

University of Electronic Science and Technology of China, Chengdu, China. Electronic address: guojinhong@sjtu.edu.cn.

Jinhong Guo (J)

School of Sensing Science and Engineering, Shanghai Jiao Tong University, Shanghai, China. Electronic address: uestc_gjc@163.com.

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Classifications MeSH