COVID-19 in Patients with Pre-Existing Interstitial Lung Disease: Potential Value of a Steroid-Based Treatment Strategy.
COVID-19
acute exacerbation
corticosteroids
interstitial lung disease
prognosis
treatment strategy
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
27 Jul 2023
27 Jul 2023
Historique:
received:
09
06
2023
revised:
23
07
2023
accepted:
25
07
2023
medline:
12
8
2023
pubmed:
12
8
2023
entrez:
12
8
2023
Statut:
epublish
Résumé
The prognosis of patients with coronavirus disease 2019 (COVID-19) and pre-existing interstitial lung disease (preILD) is poor, and no effective treatment strategy has been determined. The aim of this study was to assess the effectiveness of a steroid-based treatment strategy for patients with COVID-19 and preILD. We retrospectively reviewed the medical records of 610 consecutive patients with COVID-19 treated at our institution between 1 March 2020 and 30 October 2021 and identified 7 patients with preILD, all of whom were treated with corticosteroids and remdesivir. All the patients were men with a median age of 63 years. Three of four patients with severe disease required invasive positive-pressure ventilation (
Identifiants
pubmed: 37568341
pii: jcm12154940
doi: 10.3390/jcm12154940
pmc: PMC10419957
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Japan Society for the Promotion of Science
ID : KAKENHI grant (number JP17K09636)
Organisme : National Hospital Organization Grant
ID : H28-NHO [Kokyu]-2
Références
Virchows Arch. 2021 Jan;478(1):137-150
pubmed: 33604758
Lancet Respir Med. 2020 Jul;8(7):726-737
pubmed: 32649920
N Engl J Med. 2020 Feb 20;382(8):727-733
pubmed: 31978945
Ann Am Thorac Soc. 2021 May;18(5):799-806
pubmed: 33433263
Lancet Respir Med. 2020 Aug;8(8):807-815
pubmed: 32422178
Am J Surg Pathol. 2007 Feb;31(2):277-84
pubmed: 17255773
Intern Med. 2005 Nov;44(11):1144-50
pubmed: 16357451
N Engl J Med. 2021 Mar 4;384(9):795-807
pubmed: 33306283
Respir Investig. 2021 Nov;59(6):810-818
pubmed: 34565716
Respir Res. 2019 Dec 18;20(1):287
pubmed: 31852459
Infection. 2021 Jun;49(3):401-410
pubmed: 33389708
Am J Respir Crit Care Med. 2020 Aug 15;202(4):598-599
pubmed: 32609531
Intern Med. 2020 Dec 15;59(24):3207-3211
pubmed: 33087668
N Engl J Med. 2021 Feb 25;384(8):693-704
pubmed: 32678530
Respiration. 2021;100(6):488-498
pubmed: 33725700
Respir Res. 2014 Sep 01;15:109
pubmed: 25176016
Lancet Respir Med. 2021 Jun;9(6):665-672
pubmed: 34000237
Am J Med Sci. 2021 Jan;361(1):126-129
pubmed: 32912600
Am J Respir Crit Care Med. 2016 Aug 1;194(3):265-75
pubmed: 27299520
Respir Investig. 2021 Sep;59(5):675-678
pubmed: 34272158
BMJ Open Respir Res. 2021 Aug;8(1):
pubmed: 34376400
BMJ Open Respir Res. 2020 Sep;7(1):
pubmed: 32963028
J Intern Med. 2021 Jun;289(6):906-920
pubmed: 33274479
BMJ Open. 2019 Jan 17;9(1):e024687
pubmed: 30782739
Am J Respir Crit Care Med. 2020 Dec 15;202(12):1710-1713
pubmed: 32897754
Respirology. 2017 Oct;22(7):1363-1370
pubmed: 28508494
Gene. 2021 Jan 15;766:145145
pubmed: 32941953
Eur Respir J. 2021 Dec 9;58(6):
pubmed: 34016619
Arthritis Rheum. 1988 Mar;31(3):315-24
pubmed: 3358796
J Thorac Dis. 2020 Jul;12(7):3902-3904
pubmed: 32802476
Intern Med. 2022 Jan 15;61(2):233-236
pubmed: 34744107
Am J Respir Crit Care Med. 2021 Jan 15;203(2):245-249
pubmed: 33252997
Lung. 2022 Oct;200(5):573-577
pubmed: 36114845
N Engl J Med. 1975 Feb 13;292(7):344-7
pubmed: 1090839
Am J Respir Crit Care Med. 2018 Sep 1;198(5):e44-e68
pubmed: 30168753
Respirology. 2020 May;25(5):525-534
pubmed: 31426125
Intern Med. 2010;49(2):109-15
pubmed: 20075573
Am J Respir Crit Care Med. 2013 Sep 15;188(6):733-48
pubmed: 24032382
N Engl J Med. 2020 Jun 11;382(24):2327-2336
pubmed: 32275812
Signal Transduct Target Ther. 2022 Apr 28;7(1):141
pubmed: 35484110
Arthritis Rheum. 2010 Sep;62(9):2569-81
pubmed: 20872595
Respir Investig. 2012 Mar;50(1):3-13
pubmed: 22554854
BMJ Open Respir Res. 2021 Jul;8(1):
pubmed: 34326155
Ann Am Thorac Soc. 2021 May;18(5):773-774
pubmed: 33929309
Am J Respir Crit Care Med. 2020 Dec 15;202(12):1656-1665
pubmed: 33007173
JCI Insight. 2020 Jul 9;5(13):
pubmed: 32501293