Reversing the Inflammatory Process-25 Years of Tumor Necrosis Factor-α Inhibitors.
cytokines
immune-mediated inflammatory diseases
inflammation
liver
rheumatoid arthritis
tumor necrosis factor alpha-inhibitors
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
31 Jul 2023
31 Jul 2023
Historique:
received:
25
05
2023
revised:
25
07
2023
accepted:
28
07
2023
medline:
12
8
2023
pubmed:
12
8
2023
entrez:
12
8
2023
Statut:
epublish
Résumé
Immune-mediated inflammatory diseases, such as rheumatoid arthritis, psoriatic arthritis, peripheral and/or axial spondyloarthritis, Crohn's disease, and ulcerative colitis, are characterized by molecular and cellular changes in the immune system. Due to the systemic nature of these diseases, organs such as the liver or cardiovascular system are often affected by the inflammatory process. Tumor necrosis factor-α inhibitor therapy reduces the activation of pro-inflammatory signaling cascades, mitigates the chronic inflammatory process by restoring cellular balance, and alleviates clinical consequences, such as pain and tissue damage.
Identifiants
pubmed: 37568441
pii: jcm12155039
doi: 10.3390/jcm12155039
pmc: PMC10419406
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Subventions
Organisme : Hexal AG
ID : n.a.
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