Treatment and Prognosis of Patients with Lung Cancer and Combined Interstitial Lung Disease.

interstitial lung disease lung cancer outcome retrospective treatment

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
30 Jul 2023
Historique:
received: 27 05 2023
revised: 20 07 2023
accepted: 25 07 2023
medline: 12 8 2023
pubmed: 12 8 2023
entrez: 12 8 2023
Statut: epublish

Résumé

Interstitial lung disease (ILD) is associated with a higher lung cancer (LC) risk and may impact cancer's clinical characteristics, treatment strategies, and outcomes. This impact's extent is unclear, particularly in Caucasians. In this retrospective observational study, we reviewed the files of all LC patients diagnosed in a 38-month period. Expert radiologists reviewed the computed tomography scans performed at diagnosis. Patients with LC and ILD ( Patients with LC and ILD were older (73 ± 8 vs. 65 ± 11 years; Patients with combined LC and ILD have worse clinical outcomes even when similar treatment modalities are offered.

Sections du résumé

BACKGROUND BACKGROUND
Interstitial lung disease (ILD) is associated with a higher lung cancer (LC) risk and may impact cancer's clinical characteristics, treatment strategies, and outcomes. This impact's extent is unclear, particularly in Caucasians.
METHODS METHODS
In this retrospective observational study, we reviewed the files of all LC patients diagnosed in a 38-month period. Expert radiologists reviewed the computed tomography scans performed at diagnosis. Patients with LC and ILD (
RESULTS RESULTS
Patients with LC and ILD were older (73 ± 8 vs. 65 ± 11 years;
CONCLUSIONS CONCLUSIONS
Patients with combined LC and ILD have worse clinical outcomes even when similar treatment modalities are offered.

Identifiants

pubmed: 37568692
pii: cancers15153876
doi: 10.3390/cancers15153876
pmc: PMC10417812
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Charlotte Mauclet (C)

Division of Pulmonology, Clinique Saint-Luc Bouge, Rue Saint-Luc, 8, 5004 Namur, Belgium.

Michaël V Dupont (MV)

Division of Radiology, CHU UCL Namur (Godinne Site), Université Catholique de Louvain (UCLouvain), Avenue G. Thérasse, 1, 5530 Yvoir, Belgium.

Kerwin Roelandt (K)

Division of Radiology, CHU UCL Namur (Godinne Site), Université Catholique de Louvain (UCLouvain), Avenue G. Thérasse, 1, 5530 Yvoir, Belgium.

Maxime Regnier (M)

Scientific Support Unit, CHU UCL Namur (Godinne Site), Université Catholique de Louvain (UCLouvain), Avenue G. Thérasse, 1, 5530 Yvoir, Belgium.

Monique Delos (M)

Division of Pathology, CHU UCL Namur (Godinne Site), Université Catholique de Louvain (UCLouvain), Avenue G. Thérasse, 1, 5530 Yvoir, Belgium.

Lionel Pirard (L)

Division of Pulmonology, CHU UCL Namur (Godinne Site), Université Catholique de Louvain (UCLouvain), Avenue G. Thérasse, 1, 5530 Yvoir, Belgium.

Thierry Vander Borght (T)

Division of Nuclear Medicine, CHU UCL Namur (Godinne Site), Université Catholique de Louvain (UCLouvain), Avenue G. Thérasse, 1, 5530 Yvoir, Belgium.

Caroline Dahlqvist (C)

Division of Pulmonology, CHU UCL Namur (Godinne Site), Université Catholique de Louvain (UCLouvain), Avenue G. Thérasse, 1, 5530 Yvoir, Belgium.

Antoine Froidure (A)

Division of Pulmonology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain (UCLouvain), Avenue Hippocrate, 10, 1200 Bruxelles, Belgium.
Pole of Pulmonology, Institut de Recherche Expérimentale et Clinique (IREC), Université Catholique de Louvain (UCLouvain), Avenue Hippocrate, 55/B1.55.02, 1200 Bruxelles, Belgium.

Benoît Rondelet (B)

Division of Thoracic Surgery, CHU UCL Namur (Godinne Site), Université Catholique de Louvain (UCLouvain), Avenue G. Thérasse, 1, 5530 Yvoir, Belgium.

Jean Vanderick (J)

Division of Radiation Therapy, CHU UCL Namur (Sainte-Elisabeth Site), Université Catholique de Louvain (UCLouvain), Place Louise Godin, 15, 5000 Namur, Belgium.

Vincent Remouchamps (V)

Division of Radiation Therapy, CHU UCL Namur (Sainte-Elisabeth Site), Université Catholique de Louvain (UCLouvain), Place Louise Godin, 15, 5000 Namur, Belgium.

Fabrice Duplaquet (F)

Division of Pulmonology, CHU UCL Namur (Godinne Site), Université Catholique de Louvain (UCLouvain), Avenue G. Thérasse, 1, 5530 Yvoir, Belgium.

Sebahat Ocak (S)

Division of Pulmonology, CHU UCL Namur (Godinne Site), Université Catholique de Louvain (UCLouvain), Avenue G. Thérasse, 1, 5530 Yvoir, Belgium.
Pole of Pulmonology, Institut de Recherche Expérimentale et Clinique (IREC), Université Catholique de Louvain (UCLouvain), Avenue Hippocrate, 55/B1.55.02, 1200 Bruxelles, Belgium.

Classifications MeSH