Clinical Characteristics and Outcomes of Patients with Primary and Secondary Myelofibrosis According to the Genomic Classification Using Targeted Next-Generation Sequencing.
genomic classification
myelofibrosis
myeloproliferative neoplasms
personalized medicine
prognosis
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
31 Jul 2023
31 Jul 2023
Historique:
received:
14
06
2023
revised:
25
07
2023
accepted:
25
07
2023
medline:
12
8
2023
pubmed:
12
8
2023
entrez:
12
8
2023
Statut:
epublish
Résumé
Myelofibrosis (MF) is a heterogeneous disease regarding its mutational landscape, clinical presentation, and outcomes. The aim of our work is to evaluate the genomic classification of MF considering whether it is primary or secondary. One-hundred seventy-five patients, 81 with primary MF (PMF) and 94 with secondary MF (SMF) were hierarchically allocated into eight molecular groups. We found that
Identifiants
pubmed: 37568719
pii: cancers15153904
doi: 10.3390/cancers15153904
pmc: PMC10417554
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Instituto de Salud Carlos III
ID : FIS PI18/00205
Organisme : Instituto de Salud Carlos III
ID : PI21/00231
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