Stringent Response Factor DksA Contributes to Fatty Acid Degradation Function to Influence Cell Membrane Stability and Polymyxin B Resistance of

Polymyxin B / pharmacology Bacterial Proteins / genetics Yersinia enterocolitica / genetics Guanosine Pentaphosphate / metabolism Cell Membrane / metabolism Fatty Acids Gene Expression Regulation, Bacterial Escherichia coli Proteins / metabolism
DksA Yersinia enterocolitica fatty acid metabolism polymyxin B

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
26 Jul 2023
Historique:
received: 26 06 2023
revised: 19 07 2023
accepted: 24 07 2023
medline: 14 8 2023
pubmed: 12 8 2023
entrez: 12 8 2023
Statut: epublish

Résumé

DksA is a proteobacterial regulator that binds directly to the secondary channel of RNA polymerase with (p)ppGpp and is responsible for various bacterial physiological activities. While (p)ppGpp is known to be involved in the regulation and response of fatty acid metabolism pathways in many foodborne pathogens, the role of DksA in this process has yet to be clarified. This study aimed to characterize the function of DksA on fatty acid metabolism and cell membrane structure in

Identifiants

DOI: 10.3390/ijms241511951 PMID: 37569327 PMC: PMC10418728
pubmed: 37569327
pii: ijms241511951
doi: 10.3390/ijms241511951
pmc: PMC10418728
pii:
doi:

Substances chimiques

Polymyxin B J2VZ07J96K
Bacterial Proteins 0
Guanosine Pentaphosphate 38918-96-6
Fatty Acids 0
Escherichia coli Proteins 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Beijing Natural Science Foundation
ID : L202045
Organisme : Beijing Natural Science Foundation
ID : 6202016

Références

Mol Microbiol. 2019 Oct;112(4):1339-1349
pubmed: 31400173
J Bacteriol. 2009 May;191(10):3226-36
pubmed: 19251846
Front Microbiol. 2022 Feb 10;13:758571
pubmed: 35222323
Int J Microbiol. 2021 Sep 2;2021:1499869
pubmed: 34512763
Nat Rev Microbiol. 2012 Feb 16;10(3):203-12
pubmed: 22337166
FEMS Microbiol Rev. 2016 Jan;40(1):133-59
pubmed: 25862689
J Biol Chem. 1994 Oct 21;269(42):26584-90
pubmed: 7929384
Annu Rev Microbiol. 2008;62:35-51
pubmed: 18454629
J Mol Biol. 2001 Jan 26;305(4):673-88
pubmed: 11162084
EFSA J. 2018 Dec 12;16(12):e05500
pubmed: 32625785
Mol Microbiol. 2011 Feb;79(4):830-45
pubmed: 21299642
Cell. 1981 Dec;27(3 Pt 2):523-31
pubmed: 6086107
Methods Enzymol. 2003;371:596-601
pubmed: 14712731
FEBS Lett. 2003 Jul 31;548(1-3):90-6
pubmed: 12885413
J Bacteriol. 1990 Apr;172(4):2055-64
pubmed: 2180916
Curr Opin Microbiol. 2009 Apr;12(2):170-6
pubmed: 19318291
Cell. 2004 Aug 6;118(3):311-22
pubmed: 15294157
J Biol Chem. 1984 Feb 10;259(3):1951-7
pubmed: 6363418
Annu Rev Microbiol. 2012;66:325-47
pubmed: 22746333
Infect Immun. 2015 Nov 09;84(1):375-84
pubmed: 26553464
Int J Environ Res Public Health. 2018 Apr 26;15(5):
pubmed: 29701663
Int J Mol Sci. 2023 Apr 20;24(8):
pubmed: 37108773
Cell. 2004 Aug 6;118(3):297-309
pubmed: 15294156
Nat Commun. 2019 Dec 17;10(1):5763
pubmed: 31848343
J Biol Chem. 1973 Nov 25;248(22):7957-66
pubmed: 4147985
Annu Rev Microbiol. 2018 Sep 08;72:163-184
pubmed: 30200857
Mol Plant Pathol. 2019 Nov;20(11):1550-1565
pubmed: 31621195
Annu Rev Biochem. 1978;47:481-532
pubmed: 354502
Nature. 2005 Feb 3;433(7025):531-7
pubmed: 15690043
Nat Rev Microbiol. 2015 May;13(5):298-309
pubmed: 25853779
J Agric Food Chem. 2013 Jul 3;61(26):6574-9
pubmed: 23635088
Infect Immun. 2015 Aug;83(8):3281-92
pubmed: 26056381
Nat Rev Microbiol. 2019 Jul;17(7):417-428
pubmed: 31150012
Int J Food Microbiol. 1994 Apr;22(1):63-71
pubmed: 8060794
Int J Food Microbiol. 2019 Jan 16;289:49-56
pubmed: 30199735
J Bacteriol. 1952 Apr;63(4):505-11
pubmed: 14938323
Molecules. 2020 Dec 03;25(23):
pubmed: 33287412
Int J Food Microbiol. 2007 Apr 1;115(1):110-4
pubmed: 17196695
Microbiol Spectr. 2022 Dec 21;10(6):e0205522
pubmed: 36409141
J Bacteriol. 2002 Aug;184(16):4455-65
pubmed: 12142416
Int J Food Microbiol. 2023 Aug 2;398:110240
pubmed: 37167789
Can J Microbiol. 2002 Jul;48(7):675-80
pubmed: 12224565
Clin Microbiol Rev. 1997 Apr;10(2):257-76
pubmed: 9105754
Environ Microbiol. 2011 Mar;13(3):563-575
pubmed: 20946586
Front Microbiol. 2017 Mar 08;8:369
pubmed: 28337186
Mol Microbiol. 2007 Nov;66(4):829-39
pubmed: 17919287
J Bacteriol. 1973 Oct;116(1):355-66
pubmed: 4583220
Int J Food Microbiol. 2020 Oct 16;331:108693
pubmed: 32535524
Mol Microbiol. 2006 Nov;62(4):1048-63
pubmed: 17078815

Auteurs

Can Huang (C)

Beijing Laboratory for Food Quality and Safety, College of Food Science & Nutritional Engineering, China Agricultural University, 17 Qinghua East Rd., Beijing 100083, China.

Wenqian Li (W)

Beijing Laboratory for Food Quality and Safety, College of Food Science & Nutritional Engineering, China Agricultural University, 17 Qinghua East Rd., Beijing 100083, China.

Jingyu Chen (J)

Beijing Laboratory for Food Quality and Safety, College of Food Science & Nutritional Engineering, China Agricultural University, 17 Qinghua East Rd., Beijing 100083, China.
ORCID: 0000-0002-1348-0790

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Perforines › Peptides antimicrobiens cationiques › Polymyxines › Polymyxine B › Stringent Response Factor DksA Contributes to...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines bactériennes › Stringent Response Factor DksA Contributes to...
questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Enterobacteriaceae › Yersinia › Yersinia enterocolitica › Stringent Response Factor DksA Contributes to...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Nucléotides › Ribonucléotides › Nucléotides guanyliques › Guanosine pentaphosphate › Stringent Response Factor DksA Contributes to...
questionsmedicales.fr › Cellules › Structures cellulaires › Membrane cellulaire › Stringent Response Factor DksA Contributes to...
questionsmedicales.fr › Lipides › Acides gras › Stringent Response Factor DksA Contributes to...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Régulation de l'expression des gènes bactériens › Stringent Response Factor DksA Contributes to...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines bactériennes › Protéines Escherichia coli › Stringent Response Factor DksA Contributes to...