Genome-Wide Association Study of Lactation Traits in Chinese Holstein Cows in Southern China.
Chinese Holstein cows
genome-wide association study
high temperature and humidity
lactation traits
Journal
Animals : an open access journal from MDPI
ISSN: 2076-2615
Titre abrégé: Animals (Basel)
Pays: Switzerland
ID NLM: 101635614
Informations de publication
Date de publication:
07 Aug 2023
07 Aug 2023
Historique:
received:
25
06
2023
revised:
04
08
2023
accepted:
06
08
2023
medline:
12
8
2023
pubmed:
12
8
2023
entrez:
12
8
2023
Statut:
epublish
Résumé
Lactation traits are economically important for dairy cows. Southern China has a high-temperature and high-humidity climate, and environmental and genetic interactions greatly impact dairy cattle performance. The aim of this study was to identify novel single-nucleotide polymorphism sites and novel candidate genes associated with lactation traits in Chinese Holstein cows under high-temperature and humidity conditions in southern China. A genome-wide association study was performed for the lactation traits of 392 Chinese Holstein cows, using GGP Bovine 100 K SNP gene chips. Some 23 single nucleotide polymorphic loci significantly associated with lactation traits were screened. Among them, 16 were associated with milk fat rate, 7 with milk protein rate, and 3 with heat stress. A quantitative trait locus that significantly affects milk fat percentage in Chinese Holstein cows was identified within a window of approximately 0.5 Mb in the region of 0.4-0.9 Mb on
Identifiants
pubmed: 37570353
pii: ani13152545
doi: 10.3390/ani13152545
pmc: PMC10417049
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : GuangDong Basic and Applied Basic Research Foundation-Enterprise(Wens) Joint Fund
ID : 2019B1515210017
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