Prognostic Value of Routine Biomarkers in the Early Stage of COVID-19.

COVID-19 CRP SARS-CoV-2 biomarker eosinophil count neutrophil–lymphocyte ratio prognosis

Journal

Healthcare (Basel, Switzerland)
ISSN: 2227-9032
Titre abrégé: Healthcare (Basel)
Pays: Switzerland
ID NLM: 101666525

Informations de publication

Date de publication:
26 Jul 2023
Historique:
received: 26 06 2023
revised: 18 07 2023
accepted: 23 07 2023
medline: 12 8 2023
pubmed: 12 8 2023
entrez: 12 8 2023
Statut: epublish

Résumé

Various biomarkers like certain complete blood cell count parameters and the derived ratios including neutrophil-lymphocyte ratio are commonly used to evaluate disease severity. Our study aimed to establish if baseline levels of complete blood cell count-derived biomarkers and CRP, measured before any treatment which can interfere with their values, could serve as a predictor of development of pneumonia and the need for hospitalization requiring oxygen therapy. We retrospectively analyzed the laboratory data of 200 consecutive patients without comorbidities, who denied usage of medications prior to blood analysis and visited a COVID-19 ambulance between October and December 2021. Multivariate regression analysis extracted older age, elevated CRP and lower eosinophil count as significant independent predictors of pneumonia (

Identifiants

pubmed: 37570378
pii: healthcare11152137
doi: 10.3390/healthcare11152137
pmc: PMC10418955
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Andrea Mihajlović (A)

Department of Physiology, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21137 Novi Sad, Serbia.

David Ivanov (D)

Department of Physiology, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21137 Novi Sad, Serbia.

Borislav Tapavički (B)

Department of Physiology, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21137 Novi Sad, Serbia.

Milica Marković (M)

Health Centre Novi Sad, Bulevar Cara Lazara 75, 21102 Novi Sad, Serbia.

Dragana Vukas (D)

Health Centre Novi Sad, Bulevar Cara Lazara 75, 21102 Novi Sad, Serbia.

Ana Miljković (A)

Health Centre Novi Sad, Bulevar Cara Lazara 75, 21102 Novi Sad, Serbia.
Department of General Medicine and Geriatrics, Faculty of Medicine Novi Sad, University of Novi Sad, Hajduk Veljkova 3, 21137 Novi Sad, Serbia.

Dejana Bajić (D)

Department of Biochemistry, Faculty of Medicine Novi Sad, University of Novi Sad, Hajduk Veljkova 3, 21137 Novi Sad, Serbia.

Isidora Semnic (I)

Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21137 Novi Sad, Serbia.
Clinic of Anesthesia and Intensive Care, University Clinical Center of Vojvodina, Hajduk Veljkova 1, 21137 Novi Sad, Serbia.

Maja Bogdan (M)

Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21137 Novi Sad, Serbia.
Institute for Pulmonary Diseases of Vojvodina, Put Dr Goldmana Street 4, 21204 Sremska Kamenica, Serbia.

Dea Karaba Jakovljević (D)

Department of Physiology, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21137 Novi Sad, Serbia.

Stanislava Nikolić (S)

Department of Pathophysiology and Laboratory Medicine, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21137 Novi Sad, Serbia.
Center of Laboratory Medicine, Clinical Center of Vojvodina, Hajduk Veljkova 1, 21137 Novi Sad, Serbia.

Danijel Slavić (D)

Department of Physiology, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21137 Novi Sad, Serbia.

Dajana Lendak (D)

Department of Infectious Diseases, Faculty of Medicine, University of Novi Sad, Hajduk Veljkova 3, 21137 Novi Sad, Serbia.
Clinic for Infectious Diseases, University Clinical Center of Vojvodina, Hajduk Veljkova 1, 21137 Novi Sad, Serbia.

Classifications MeSH