Does a Gluten-Free Diet Improve Quality of Life and Sleep in Patients with Non-Coeliac Gluten/Wheat Sensitivity?

Coeliac Disease NCGWS Non-Coeliac Gluten/Wheat Sensitivity gluten-free diet quality of life sleep

Journal

Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595

Informations de publication

Date de publication:
04 Aug 2023
Historique:
received: 12 07 2023
revised: 29 07 2023
accepted: 01 08 2023
medline: 14 8 2023
pubmed: 12 8 2023
entrez: 12 8 2023
Statut: epublish

Résumé

The role of a gluten-free diet (GFD) in Non-Coeliac Gluten/Wheat Sensitivity (NCGWS) is unclear. We present the largest study comparing adherence to a GFD in patients with Coeliac Disease (CD) and NCGWS and assess its impact on quality of life (QoL) and sleep in patients with NCGWS. Patients with NCGWS at a tertiary centre completed the Coeliac Disease Adherence Test (CDAT), Coeliac Symptom Index (CSI) and Sleep Condition Indicator (SCI). Higher CDAT scores indicate worse adherence, higher CSI scores indicate poorer QoL, and higher SCI scores indicate better sleep. CDAT scores were correlated with CSI and SCI scores. A second group of patients with CD completed the CDAT questionnaire only. Results were compared with the CDAT responses from the NCGWS group. For the NCGWS cohort ( Patients with NCGWS adhere to a GFD less than those with CD. Poorer adherence to a GFD in patients with NCGWS correlates with a worse QoL and sleep performance.

Identifiants

pubmed: 37571398
pii: nu15153461
doi: 10.3390/nu15153461
pmc: PMC10421138
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Connor Cotton (C)

Academic Unit of Gastroenterology, Sheffield Teaching Hospitals, Sheffield S10 2JF, UK.

Suneil A Raju (SA)

Academic Unit of Gastroenterology, Sheffield Teaching Hospitals, Sheffield S10 2JF, UK.
Department of Infection, Immunity and Cardiovascular Disease, The University of Sheffield, Sheffield S10 2TN, UK.

Hamza Ahmed (H)

Academic Unit of Gastroenterology, Sheffield Teaching Hospitals, Sheffield S10 2JF, UK.

Grace Webster (G)

Academic Unit of Gastroenterology, Sheffield Teaching Hospitals, Sheffield S10 2JF, UK.

Rachel Hallam (R)

Academic Unit of Gastroenterology, Sheffield Teaching Hospitals, Sheffield S10 2JF, UK.

Iain Croall (I)

Department of Infection, Immunity and Cardiovascular Disease, The University of Sheffield, Sheffield S10 2TN, UK.
Academic Unit of Radiology, University of Sheffield, Sheffield S10 2TN, UK.

Sarah Coleman (S)

Academic Unit of Gastroenterology, Sheffield Teaching Hospitals, Sheffield S10 2JF, UK.

Nick Trott (N)

Academic Unit of Gastroenterology, Sheffield Teaching Hospitals, Sheffield S10 2JF, UK.
Department of Infection, Immunity and Cardiovascular Disease, The University of Sheffield, Sheffield S10 2TN, UK.

Anupam Rej (A)

Academic Unit of Gastroenterology, Sheffield Teaching Hospitals, Sheffield S10 2JF, UK.

Mohamed G Shiha (MG)

Academic Unit of Gastroenterology, Sheffield Teaching Hospitals, Sheffield S10 2JF, UK.
Department of Infection, Immunity and Cardiovascular Disease, The University of Sheffield, Sheffield S10 2TN, UK.

Imran Aziz (I)

Academic Unit of Gastroenterology, Sheffield Teaching Hospitals, Sheffield S10 2JF, UK.
Department of Infection, Immunity and Cardiovascular Disease, The University of Sheffield, Sheffield S10 2TN, UK.

David S Sanders (DS)

Academic Unit of Gastroenterology, Sheffield Teaching Hospitals, Sheffield S10 2JF, UK.
Department of Infection, Immunity and Cardiovascular Disease, The University of Sheffield, Sheffield S10 2TN, UK.

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