Reliable long-term organ cryopreservation makes donor organ bank a feasible reality.


Journal

Artificial organs
ISSN: 1525-1594
Titre abrégé: Artif Organs
Pays: United States
ID NLM: 7802778

Informations de publication

Date de publication:
Sep 2023
Historique:
medline: 28 9 2023
pubmed: 12 8 2023
entrez: 12 8 2023
Statut: ppublish

Résumé

Long-term donor organ preservation has been sought after since the beginning of transplantation. Static cold storage is the gold standard for organ transport but is limited to short-term preservation because of the inability to maintain subfreezing temperatures without harmful ice cyrstal formation. Recent developments in cryopreservation via vitrification and nanowarming have demonstrated reliable storage and restoration of healthy donor organs without ice crystallization.

Identifiants

pubmed: 37571816
doi: 10.1111/aor.14629
doi:

Substances chimiques

Ice 0

Types de publication

News

Langues

eng

Sous-ensembles de citation

IM

Pagination

1421-1422

Informations de copyright

© 2023 International Center for Artificial Organ and Transplantation (ICAOT) and Wiley Periodicals LLC.

Références

Han Z, Rao JS, Gangwar L, Namsrai BE, Pasek-Allen JL, Etheridge ML, et al. Vitrification and nanowarming enable long-term organ cryopreservation and life-sustaining kidney transplantation in a rat model. Nat Commun. 2023;14:3407. https://doi.org/10.1038/s41467-023-38824-8
Jing L, Yao L, Zhao M, Peng LP, Liu M. Organ preservation: from the past to the future. Acta Pharmacol Sin. 2018;39:845-857. https://doi.org/10.1038/aps.2017.182
Collins GM, Bravo-Shugarman M, Terasaki PI. Kidney preservation for transportation. Initial perfusion and 30 hours' ice storage. Lancet. 1969;2(7632):1219-1222. https://doi.org/10.1016/s0140-6736(69)90753-3
Manuchehrabadi N, Gao Z, Zhang J, Ring HL, Shao Q, Liu F, et al. Improved tissue cryopreservation using inductive heating of magnetic nanoparticles. Sci Transl Med. 2017;9:eaah4586.

Auteurs

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Classifications MeSH