Point prevalence survey of antibiotic use and healthcare-associated infections in acute care hospitals: a comprehensive report from the Marche Region of Italy.

Acute care hospitals Antibiotic resistance Antibiotic stewardship Healthcare-associated infection Infection control Point prevalence survey Surveillance

Journal

The Journal of hospital infection
ISSN: 1532-2939
Titre abrégé: J Hosp Infect
Pays: England
ID NLM: 8007166

Informations de publication

Date de publication:
Nov 2023
Historique:
received: 23 05 2023
revised: 01 07 2023
accepted: 10 07 2023
medline: 7 11 2023
pubmed: 14 8 2023
entrez: 13 8 2023
Statut: ppublish

Résumé

Healthcare-associated infections (HAIs) and antimicrobial resistance (AMR) are serious health challenges. Point prevalence surveys (PPSs) are valuable tools for monitoring HAIs and AMR. To describe results of the ECDC PPS 2022 dealing with the prevalence of HAIs, antimicrobial consumption, and associated factors, in acute care hospitals. The survey was performed in November 2022 in 14 hospitals according to the protocol proposed by the European Centre for Disease Prevention and Control. Multilevel logistic regression was performed using geographical area/hospital type as cluster variable to evaluate the factors independently associated with HAIs and antibiotics. The point prevalence of HAIs was 7.43%. Patients hospitalized for longer periods were more likely to have an HAI as well as those aged 15-44 years, with a rapidly fatal disease, intubated, and with one or two devices. Antibiotics prevalence was 47.30%. Males, unknown McCabe scores, minimally invasive/non-National Healthcare Safety Network (NHSN) surgery, patients with HAIs, hospitals with a higher alcohol hand-rub consumption, hospitals with a greater number of IPC personnel, geriatric wards, and hospitals with 300-600 beds were more likely to be under antimicrobial therapy. This PPS provided valuable information on the prevalence of HAIs and antimicrobial consumption and variables associated. The high prevalence of HAIs highlights the need for improved infection control measures.

Sections du résumé

BACKGROUND BACKGROUND
Healthcare-associated infections (HAIs) and antimicrobial resistance (AMR) are serious health challenges. Point prevalence surveys (PPSs) are valuable tools for monitoring HAIs and AMR.
AIM OBJECTIVE
To describe results of the ECDC PPS 2022 dealing with the prevalence of HAIs, antimicrobial consumption, and associated factors, in acute care hospitals.
METHODS METHODS
The survey was performed in November 2022 in 14 hospitals according to the protocol proposed by the European Centre for Disease Prevention and Control. Multilevel logistic regression was performed using geographical area/hospital type as cluster variable to evaluate the factors independently associated with HAIs and antibiotics.
FINDINGS RESULTS
The point prevalence of HAIs was 7.43%. Patients hospitalized for longer periods were more likely to have an HAI as well as those aged 15-44 years, with a rapidly fatal disease, intubated, and with one or two devices. Antibiotics prevalence was 47.30%. Males, unknown McCabe scores, minimally invasive/non-National Healthcare Safety Network (NHSN) surgery, patients with HAIs, hospitals with a higher alcohol hand-rub consumption, hospitals with a greater number of IPC personnel, geriatric wards, and hospitals with 300-600 beds were more likely to be under antimicrobial therapy.
CONCLUSION CONCLUSIONS
This PPS provided valuable information on the prevalence of HAIs and antimicrobial consumption and variables associated. The high prevalence of HAIs highlights the need for improved infection control measures.

Identifiants

pubmed: 37574019
pii: S0195-6701(23)00259-1
doi: 10.1016/j.jhin.2023.07.025
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0
Anti-Infective Agents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

80-87

Investigateurs

A M Schimizzi (AM)
A Baldassarri (A)
D Vincitorio (D)
M Biondi (M)
P Ferretti (P)
S Maestri (S)
E Draghi (E)
D Arsego (D)
L Ferrara (L)
M Vittorio (M)
M Capasso (M)
C Di Falco (C)
G Scaloni (G)
M Di Febbo (M)
A Aguzzi (A)
V Benigni (V)
M Tavio (M)
A Marigliano (A)
A Rinaldi (A)
A Marcello (A)
A Mazzacchera (A)
A Serafini (A)
A Genga (A)
C D Giorgio Mangino (CD)
C Vesprini (C)
D Barbaresi (D)
D Scutti (D)
E Mali (E)
G M Semprini (GM)
G Marchini (G)
G M Ricciotti (GM)
G Mercante (G)
G Paolorossi (G)
M I Faggi (MI)
L Gatti (L)
M Uncini (M)
O D Toscano (OD)
P Sabatini (P)
S Rosati (S)
S Bizzarri (S)
T Poggioli (T)
I Garota (I)
M E Pertosa (ME)
M R Mazzoccanti (MR)

Informations de copyright

Copyright © 2023 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Auteurs

P Barbadoro (P)

Department of Biomedical Sciences and Public Health, Section of Hygiene, Preventive Medicine and Public Health, Polytechnic University of the Marche Region, Ancona, Italy.

J Dolcini (J)

Department of Biomedical Sciences and Public Health, Section of Hygiene, Preventive Medicine and Public Health, Polytechnic University of the Marche Region, Ancona, Italy. Electronic address: j.dolcini@staff.univpm.it.

C Fortunato (C)

Department of Biomedical Sciences and Public Health, Section of Hygiene, Preventive Medicine and Public Health, Polytechnic University of the Marche Region, Ancona, Italy.

D Mengarelli Detto Rinaldini (D)

Department of Biomedical Sciences and Public Health, Section of Hygiene, Preventive Medicine and Public Health, Polytechnic University of the Marche Region, Ancona, Italy.

E Martini (E)

Hospital Hygiene Unit, Azienda Ospedaliero-Universitaria Ospedali Riuniti, Ancona, Italy.

M G Gioia (MG)

Hospital Hygiene Unit, Azienda Ospedaliero-Universitaria Ospedali Riuniti, Ancona, Italy.

D Mengoni (D)

Hospital Hygiene Unit, Azienda Ospedaliero-Universitaria Ospedali Riuniti, Ancona, Italy.

M M D'Errico (MM)

Department of Biomedical Sciences and Public Health, Section of Hygiene, Preventive Medicine and Public Health, Polytechnic University of the Marche Region, Ancona, Italy.

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Classifications MeSH