A multicomponent holistic care pathway for people who use drugs in Tayside, Scotland.

Community Hepatitis c virus Holistic People who use drugs

Journal

The International journal on drug policy
ISSN: 1873-4758
Titre abrégé: Int J Drug Policy
Pays: Netherlands
ID NLM: 9014759

Informations de publication

Date de publication:
Oct 2023
Historique:
received: 31 01 2023
revised: 31 07 2023
accepted: 01 08 2023
pubmed: 14 8 2023
medline: 14 8 2023
entrez: 14 8 2023
Statut: ppublish

Résumé

People Who Use Drugs (PWUD) are at high risk of non-fatal overdose and other drug-related harms. The United Kingdom drugs policy landscape makes it challenging to support those at risk. Tayside, in East Scotland, has a sizeable population at risk of drug-related harms. In 2021, the National Health Service implemented a care pathway for PWUD to provide multidimensional healthcare interventions. We aimed to quantify drug-related harms; assess wider health and well-being; and understand substance use trends and behaviours, among those engaged in the pathway. Existing community-embedded blood-borne virus pathways were adapted to provide multiple healthcare assessments over three visits. We undertook an observational cohort study to analyse uptake and outcomes for the initial cohort of PWUD engaged at appointment one. From August 2021-September 2022, 150 PWUD engaged with the pathway. Median age was 39 (34-42) years, 108 (72%) were male, and 124 (83%) lived in deprived areas. Seventy (47%) had been disengaged from healthcare for over a year. Polysubstance use was reported by 124 (83%), 42 (28%) disclosed injecting daily, and 54 (36%) shared equipment. Fifty-four (36%) experienced recent non-fatal overdose, and there were six overdose fatalities (4.1 [1.5-9.0] per 100PY). The offer of take-home naloxone was accepted by 108 (72%). Fourteen (9%) were diagnosed with Hepatitis C and two (1%) with HIV. Renal, hepatological, and endocrine impairment were observed among 30 (20%), 23 (15%), and 11 (7%), people respectively. Ninety-six (65%) had high risk of clinical depression. Forty-eight (32%) declined Covid-19 vaccination. The pathway engaged PWUD with high exposure to recent non-fatal overdose and other drug-related harms, alongside co-morbid health issues. Our results suggest multi-dimensional health assessments coupled with harm reduction in community settings, with appropriate linkage to care, are warranted for PWUD. Service commissioners should seek to integrate these assessments where possible.

Sections du résumé

BACKGROUND BACKGROUND
People Who Use Drugs (PWUD) are at high risk of non-fatal overdose and other drug-related harms. The United Kingdom drugs policy landscape makes it challenging to support those at risk. Tayside, in East Scotland, has a sizeable population at risk of drug-related harms. In 2021, the National Health Service implemented a care pathway for PWUD to provide multidimensional healthcare interventions. We aimed to quantify drug-related harms; assess wider health and well-being; and understand substance use trends and behaviours, among those engaged in the pathway.
METHODS METHODS
Existing community-embedded blood-borne virus pathways were adapted to provide multiple healthcare assessments over three visits. We undertook an observational cohort study to analyse uptake and outcomes for the initial cohort of PWUD engaged at appointment one.
RESULTS RESULTS
From August 2021-September 2022, 150 PWUD engaged with the pathway. Median age was 39 (34-42) years, 108 (72%) were male, and 124 (83%) lived in deprived areas. Seventy (47%) had been disengaged from healthcare for over a year. Polysubstance use was reported by 124 (83%), 42 (28%) disclosed injecting daily, and 54 (36%) shared equipment. Fifty-four (36%) experienced recent non-fatal overdose, and there were six overdose fatalities (4.1 [1.5-9.0] per 100PY). The offer of take-home naloxone was accepted by 108 (72%). Fourteen (9%) were diagnosed with Hepatitis C and two (1%) with HIV. Renal, hepatological, and endocrine impairment were observed among 30 (20%), 23 (15%), and 11 (7%), people respectively. Ninety-six (65%) had high risk of clinical depression. Forty-eight (32%) declined Covid-19 vaccination.
CONCLUSION CONCLUSIONS
The pathway engaged PWUD with high exposure to recent non-fatal overdose and other drug-related harms, alongside co-morbid health issues. Our results suggest multi-dimensional health assessments coupled with harm reduction in community settings, with appropriate linkage to care, are warranted for PWUD. Service commissioners should seek to integrate these assessments where possible.

Identifiants

pubmed: 37574644
pii: S0955-3959(23)00206-2
doi: 10.1016/j.drugpo.2023.104159
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

104159

Informations de copyright

Copyright © 2023 The Author(s). Published by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest C.J.B. has received honoraria from the International Network on Health and Hepatitis in Substance Users (INHSU), unrelated to the submitted work. A.R. declares receipt of research grants from Abbvie, BMS, Pfizer and Gilead. Lecture fees and honorariums from Abbvie and Gilead, unrelated to the submitted work. E.F. and D.T. declare no conflicts. B.P.S. has received honoraria for lectures from Janssen-Cilag, Merck Sharp & Dohme and Gilead Sciences, unrelated to the submitted work. J.F.D. declares receipt of research grants, lecture fees and honorariums from Abbvie, BMS, Gilead, MSD, and Roche, unrelated to the submitted work.

Auteurs

Christopher J Byrne (CJ)

Division of Molecular and Clinical Medicine, University of Dundee, Dundee, Scotland; Directorate of Public Health, Kings Cross Hospital, NHS Tayside, Dundee, Scotland. Electronic address: c.x.byrne@dundee.ac.uk.

Andrew Radley (A)

Division of Molecular and Clinical Medicine, University of Dundee, Dundee, Scotland; Directorate of Public Health, Kings Cross Hospital, NHS Tayside, Dundee, Scotland.

Emma Fletcher (E)

Directorate of Public Health, Kings Cross Hospital, NHS Tayside, Dundee, Scotland.

Donna Thain (D)

Directorate of Public Health, Kings Cross Hospital, NHS Tayside, Dundee, Scotland.

Brian P Stephens (BP)

Department of Gastroenterology, Ninewells Hospital and Medical School, NHS Tayside, Dundee, Scotland.

John F Dillon (JF)

Division of Molecular and Clinical Medicine, University of Dundee, Dundee, Scotland; Department of Gastroenterology, Ninewells Hospital and Medical School, NHS Tayside, Dundee, Scotland.

Classifications MeSH