Recent Advances in the Development of Near-Infrared Fluorescent Probes for the
Alzheimer’s disease
diagnosis
donor-π-acceptor
in vivo imaging
near-infrared fluorescent probes
β-amyloid (Aβ) species
Journal
ACS chemical neuroscience
ISSN: 1948-7193
Titre abrégé: ACS Chem Neurosci
Pays: United States
ID NLM: 101525337
Informations de publication
Date de publication:
06 09 2023
06 09 2023
Historique:
medline:
7
9
2023
pubmed:
14
8
2023
entrez:
14
8
2023
Statut:
ppublish
Résumé
The deposition of β-amyloid (Aβ) plaques in the parenchymal and cortical regions of the brain of Alzheimer's disease (AD) patients is considered the foremost pathological hallmark of the disease. The early diagnosis of AD is paramount in order to effective management and treatment of the disease. Developing near-infrared fluorescence (NIRF) probes targeting Aβ species is a potential and attractive approach suitable for the early and timely diagnosis of AD. The advantages of the NIRF probes over other tools include real-time detection, higher sensitivity, resolution, comparatively inexpensive experimental setup, and noninvasive nature. Currently, enormous progress is being observed in the development of NIRF probes for the
Identifiants
pubmed: 37574911
doi: 10.1021/acschemneuro.3c00304
doi:
Substances chimiques
Fluorescent Dyes
0
Amyloid beta-Peptides
0
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM