Presenilins and mitochondria-an intriguing link: mini-review.
Alzheimer’s disease
mitochondria associated membranes
neurodegeneration
presenilins
spine apparatus
Journal
Frontiers in neuroscience
ISSN: 1662-4548
Titre abrégé: Front Neurosci
Pays: Switzerland
ID NLM: 101478481
Informations de publication
Date de publication:
2023
2023
Historique:
received:
29
06
2023
accepted:
14
07
2023
medline:
14
8
2023
pubmed:
14
8
2023
entrez:
14
8
2023
Statut:
epublish
Résumé
This review uncovers the intricate relationship between presenilins, calcium, and mitochondria in the context of Alzheimer's disease (AD), with a particular focus on the involvement of presenilin mutations in mitochondrial dysfunction. So far, it is unclear whether the impairment of mitochondrial function arises primarily from damage inflicted by
Identifiants
pubmed: 37575294
doi: 10.3389/fnins.2023.1249815
pmc: PMC10416233
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
1249815Informations de copyright
Copyright © 2023 Makarov, Kushnireva, Papa and Korkotian.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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