Local Methotrexate Plus Uterine Artery Embolization for High-Risk Interstitial Ectopic Pregnancy.

interstitial ectopic pregnancy interventional radiology methotrexate uterine artery embolization

Journal

Seminars in interventional radiology
ISSN: 0739-9529
Titre abrégé: Semin Intervent Radiol
Pays: United States
ID NLM: 8510974

Informations de publication

Date de publication:
Aug 2023
Historique:
pmc-release: 10 08 2024
medline: 14 8 2023
pubmed: 14 8 2023
entrez: 14 8 2023
Statut: epublish

Résumé

Interstitial ectopic pregnancy involves the interstitial portion of the fallopian tube and is among the most hazardous of all ectopic pregnancies, with the highest risk of uterine rupture and maternal mortality. Unlike tubal ectopic pregnancy, management of interstitial pregnancy is not well standardized. Systemic methotrexate (MTX) and surgical resection are the primary treatment options; however, failure rates and risk of bleeding remain high. Alternative minimally invasive techniques have been described-including uterine artery embolization (UAE) and local injection of MTX or potassium chloride-and may confer improved success rates. We report a case of a high-risk 28-year-old female with an interstitial ectopic pregnancy successfully treated with combined local injection of MTX plus UAE. We describe our technique and the unique medical management in the setting of a known bleeding disorder.

Identifiants

pubmed: 37575342
doi: 10.1055/s-0043-1770712
pii: sir001487
pmc: PMC10415050
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

357-361

Informations de copyright

Thieme. All rights reserved.

Déclaration de conflit d'intérêts

Conflicts of Interest None declared.

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Auteurs

Mark Mikhitarian (M)

Department of Radiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina.

William Goodnight Iii (W)

Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, North Carolina.

Nicole Keefe (N)

Department of Radiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina.

Classifications MeSH