Mycologically confirmed chronic pulmonary aspergillosis in a post-pulmonary tuberculosis patient in Ghana.


Journal

Ghana medical journal
ISSN: 2616-163X
Titre abrégé: Ghana Med J
Pays: Ghana
ID NLM: 0073210

Informations de publication

Date de publication:
Dec 2022
Historique:
medline: 15 8 2023
pubmed: 14 8 2023
entrez: 14 8 2023
Statut: ppublish

Résumé

Pulmonary tuberculosis (PTB) remains a major public health challenge in low- and middle-income countries. PTB may leave residual cavitation following treatment in some patients, allowing saprophytic colonization by Aspergillus species, resulting in a slow, progressive lung condition known as chronic pulmonary aspergillosis (CPA). PTB is the commonest underlying condition in CPA, mainly post-treatment. CPA is likely to be misdiagnosed as PTB reactivation due to clinical and radiological similarities. Ghana has a significant PTB burden, but only one case of clinically and radiologically diagnosed CPA has been reported, and epidemiological studies are also lacking. The definitive diagnosis of CPA comprises symptomatology, imaging findings and mycological evidence. Mycological evidence is critical to rule out other differential diagnoses, including non- Fungal laboratory testing was provided by a CARIGEST SA studentship and research award to BKO and DWD respectively.

Identifiants

pubmed: 37575628
doi: 10.4314/gmj.v56i4.13
pii: jGMJ.v56.i4.pg336
pmc: PMC10416292
doi:

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

336-339

Informations de copyright

Copyright © The Author(s).

Déclaration de conflit d'intérêts

Conflict of interest: None declared

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Auteurs

Bright K Ocansey (BK)

Division of Evolution, Infection and Genomics, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.

Abraham Adjei (A)

Chest Clinic, Department of Medicine and Therapeutics, Korle-Bu Teaching Hospital, Accra, Ghana.

David W Denning (DW)

Division of Evolution, Infection and Genomics, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.

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Classifications MeSH