Tumefactive Multiple Sclerosis: Challenges With Treatment Modalities.
diagnosis of multiple sclerosis
high-dose corticosteroids
intravenous immunoglobulins (ivig)
multiple sclerosis flare-up
tumefactive sclerosis
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Jul 2023
Jul 2023
Historique:
accepted:
13
07
2023
medline:
14
8
2023
pubmed:
14
8
2023
entrez:
14
8
2023
Statut:
epublish
Résumé
Tumefactive multiple sclerosis comprises a rare subset of multiple sclerosis that often poses a diagnostic challenge to physicians. It is unique in its presentation as a solitary lesion, usually larger than 2 cm, with surrounding vasogenic edema, commonly mimicking a primary intracranial malignancy. We present a case of a 25-year-old female with no significant past medical history who presented to our institution with homonymous superior quadrantanopia. During her admission, she underwent a magnetic resonance imaging (MRI) of the brain, which revealed a large lesion in the left temporal area surrounded by marked edema. A thorough workup revealed a diagnosis of tumefactive multiple sclerosis. Subsequently, she was initiated on intravenous immunoglobulin rather than stress dose steroids, given the concern for a superimposed infection. Interestingly, the patient had a paradoxical progression of her symptoms as well as expansion of the vasogenic edema on a repeat MRI. In our case, we highlight the key differences in tumefactive multiple sclerosis diagnosis and management.
Identifiants
pubmed: 37575699
doi: 10.7759/cureus.41845
pmc: PMC10423083
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e41845Informations de copyright
Copyright © 2023, ElSaygh et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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