An observational analysis of risk factors associated with symptomatic third molar teeth.
ALSPAC
Third molars
genetics
pericoronitis
risk factors
wisdom teeth
Journal
Wellcome open research
ISSN: 2398-502X
Titre abrégé: Wellcome Open Res
Pays: England
ID NLM: 101696457
Informations de publication
Date de publication:
2022
2022
Historique:
accepted:
28
06
2023
medline:
14
8
2023
pubmed:
14
8
2023
entrez:
14
8
2023
Statut:
epublish
Résumé
Third molar teeth (wisdom teeth) are a common cause of pain and infection in young adults. The study aimed to describe the prevalence of symptomatic third molar teeth and identify factors which predispose to third molar symptoms in a birth cohort. An observational study was undertaken nested in the Avon Longitudinal Study of Parents and Children (ALSPAC), a birth cohort based in south west England. The main outcomes were self-reported third molar pain, swelling and treatment for third molar problems, taken from questionnaires completed at age 23 years. The exposures including sex, dental history, socioeconomic status, diet, and genetic factors were obtained from earlier ALSPAC data. In total 4,222 ALSPAC participants responded to one or more questions about third molar teeth. The final sample included more female participants than male participants. The majority of participants (56.6%) reported at least one episode of pain associated with their third molars. Females had greater odds than males of reporting swelling (adjusted odds ratio (OR) 1.97; 95%confidence interval (CI) 1.56, 2.51), pain (adjusted OR=1.96; 95%CI 1.56, 2.51) and receiving both non-surgical and surgical treatment (adjusted OR=2.30; 95%CI 1.62, 3.35, adjusted OR=1.54; 95%CI 1.17, 2.06 respectively). Participants with previously filled teeth had greater odds of third molar extraction. There were no strong associations between index of multiple deprivation (IMD) score or sugar intake and the third molar outcomes. There was weak evidence for a genetic contribution to third molar pain. Symptomatic third molars are common in this age group, with over half of the participants reporting pain or other symptoms. Female participants had greater odds for third molar pain, swelling and treatment.
Sections du résumé
BACKGROUND
BACKGROUND
Third molar teeth (wisdom teeth) are a common cause of pain and infection in young adults. The study aimed to describe the prevalence of symptomatic third molar teeth and identify factors which predispose to third molar symptoms in a birth cohort.
METHODS
METHODS
An observational study was undertaken nested in the Avon Longitudinal Study of Parents and Children (ALSPAC), a birth cohort based in south west England. The main outcomes were self-reported third molar pain, swelling and treatment for third molar problems, taken from questionnaires completed at age 23 years. The exposures including sex, dental history, socioeconomic status, diet, and genetic factors were obtained from earlier ALSPAC data.
RESULTS
RESULTS
In total 4,222 ALSPAC participants responded to one or more questions about third molar teeth. The final sample included more female participants than male participants. The majority of participants (56.6%) reported at least one episode of pain associated with their third molars. Females had greater odds than males of reporting swelling (adjusted odds ratio (OR) 1.97; 95%confidence interval (CI) 1.56, 2.51), pain (adjusted OR=1.96; 95%CI 1.56, 2.51) and receiving both non-surgical and surgical treatment (adjusted OR=2.30; 95%CI 1.62, 3.35, adjusted OR=1.54; 95%CI 1.17, 2.06 respectively). Participants with previously filled teeth had greater odds of third molar extraction. There were no strong associations between index of multiple deprivation (IMD) score or sugar intake and the third molar outcomes. There was weak evidence for a genetic contribution to third molar pain.
CONCLUSIONS
CONCLUSIONS
Symptomatic third molars are common in this age group, with over half of the participants reporting pain or other symptoms. Female participants had greater odds for third molar pain, swelling and treatment.
Identifiants
pubmed: 37577450
doi: 10.12688/wellcomeopenres.17673.2
pmc: PMC10422052
doi:
Banques de données
figshare
['10.6084/m9.figshare.19188224.v1']
Types de publication
Journal Article
Langues
eng
Pagination
71Informations de copyright
Copyright: © 2023 Bruce D et al.
Déclaration de conflit d'intérêts
No competing interests were disclosed.
Références
J Oral Maxillofac Surg. 2010 May;68(5):990-5
pubmed: 20096980
J Oral Maxillofac Surg. 2012 Sep;70(9 Suppl 1):S15-9
pubmed: 22717377
Quintessence Int. 2011 Jun;42(6):445-53
pubmed: 21519580
Br J Oral Maxillofac Surg. 2019 May;57(4):306-311
pubmed: 30952374
Am J Public Health. 2007 Sep;97(9):1554-9
pubmed: 17666691
Int J Epidemiol. 2013 Feb;42(1):111-27
pubmed: 22507743
J Dent Res. 2008 Jan;87(1):60-4
pubmed: 18096895
Braz Dent J. 1998;9(2):91-4
pubmed: 10219121
Atlas Oral Maxillofac Surg Clin North Am. 2012 Sep;20(2):159-62
pubmed: 23021392
Br Dent J. 2002 Dec 21;193(12):697-702; discussion 695
pubmed: 12529726
Cochrane Database Syst Rev. 2020 May 4;5:CD003879
pubmed: 32368796
Health Technol Assess. 2020 Jun;24(30):1-116
pubmed: 32589125
Lancet. 2007 Jan 6;369(9555):51-9
pubmed: 17208642
J Biomed Inform. 2009 Apr;42(2):377-81
pubmed: 18929686
J Dent Res. 2015 Jul;94(7):886-94
pubmed: 25883107
Am J Hum Genet. 2011 Mar 11;88(3):294-305
pubmed: 21376301
JDR Clin Trans Res. 2019 Oct;4(4):333-341
pubmed: 31039050
J Oral Maxillofac Surg. 2003 Jul;61(7):759-63; discussion 764-5
pubmed: 12856246
Community Dent Health. 2014 Jun;31(2):111-6
pubmed: 25055609
Br J Gen Pract. 2016 Aug;66(649):e606-8
pubmed: 27481985
J Anat. 2019 May;234(5):709-717
pubmed: 30834524
J Forensic Dent Sci. 2017 Sep-Dec;9(3):130-134
pubmed: 29657489
Br Dent J. 2013 Sep;215(5):209-12
pubmed: 24029981
Clin Oral Investig. 2019 May;23(5):2443-2453
pubmed: 30311061
J Oral Maxillofac Surg. 2015 Jan;73(1):7-12
pubmed: 25262404
Aust Dent J. 2007 Sep;52(3):205-9
pubmed: 17969289
Am J Hum Genet. 2011 Jan 7;88(1):76-82
pubmed: 21167468
Nat Rev Genet. 2002 Nov;3(11):872-82
pubmed: 12415317
Br Dent J. 2009 Sep 12;207(5):E10; discussion 218-9
pubmed: 19730432
Community Dent Health. 2018 Nov 29;35(4):217-222
pubmed: 30188616
Int J Epidemiol. 2013 Feb;42(1):97-110
pubmed: 22507742
Arch Oral Biol. 2009 Dec;54 Suppl 1:S45-51
pubmed: 18715551
J Oral Maxillofac Surg. 2012 Sep;70(9 Suppl 1):S48-57
pubmed: 22762969
Nat Genet. 2017 Aug 30;49(9):1304-1310
pubmed: 28854176
Br J Oral Maxillofac Surg. 2014 Feb;52(2):185-9
pubmed: 24314915
Wellcome Open Res. 2019 Mar 14;4:51
pubmed: 31020050
Community Dent Oral Epidemiol. 2018 Oct;46(5):457-464
pubmed: 30125961
Int J Epidemiol. 2018 Aug 1;47(4):1207-1216
pubmed: 29800128
Br Dent J. 2012 Sep;213(5):E8
pubmed: 22955790
Stomatologija. 2015;17(1):3-8
pubmed: 26183851
J Periodontol. 2011 Apr;82(4):558-65
pubmed: 20936916
J Ir Dent Assoc. 2009 Aug-Sep;55(4):190-2
pubmed: 19753908
J Oral Maxillofac Surg. 2007 Sep;65(9):1685-92
pubmed: 17719384
Nat Methods. 2011 Dec 04;9(2):179-81
pubmed: 22138821