Biocompatible Gallium Nanodots against Drug-Resistant Bacterial Pneumonia and Liver Abscess.

Humans Gallium / pharmacology Escherichia coli Anti-Bacterial Agents / pharmacology Bacteria Pneumonia, Bacterial Liver Abscess Microbial Sensitivity Tests
antibacterial effect biocompatible nanomaterials drug-resistant bacteria gallium nanoparticles inflammation

Journal

ACS applied materials & interfaces
ISSN: 1944-8252
Titre abrégé: ACS Appl Mater Interfaces
Pays: United States
ID NLM: 101504991

Informations de publication

Date de publication:
23 Aug 2023
Historique:
medline: 25 8 2023
pubmed: 14 8 2023
entrez: 14 8 2023
Statut: ppublish

Résumé

Resistant bacterial infection remains a severe public health threat, and conventional antibiotic drugs work poorly in effectively treating infectious diseases. Here, we developed gallium-based nanodots (Ga NDs), consisting of specific disruption of bacterial iron ability, to treat multidrug-resistant (MDR) Gram-negative bacteria-infected diseases. The Ga NDs significantly suppress the proliferation of two typical MDR bacteria strains (

Identifiants

DOI: 10.1021/acsami.3c07256 PMID: 37579188
pubmed: 37579188
doi: 10.1021/acsami.3c07256
doi:

Substances chimiques

Gallium CH46OC8YV4
Anti-Bacterial Agents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

39143-39156

Auteurs

Yuchen Qi (Y)

Eye Center, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 223300, P. R. China.
Zhejiang University-University of Edinburgh Institute (ZJU-UoE Institute), Zhejiang University School of Medicine, Zhejiang University, Haining 314400, P. R. China.

Yangyang Li (Y)

Eye Center, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 223300, P. R. China.

Kun Li (K)

Department of Musculoskeletal Oncology, Fudan University Shanghai Cancer Center, Shanghai 210000, P. R. China.

Tingting Xie (T)

Zhejiang University-University of Edinburgh Institute (ZJU-UoE Institute), Zhejiang University School of Medicine, Zhejiang University, Haining 314400, P. R. China.

Shiyuan Hua (S)

Eye Center, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 223300, P. R. China.

Qunfeng Guo (Q)

Department of Orthopedics, Shanghai Changzheng Hospital, Naval Medical University, Shanghai 200003, P. R. China.

Yichun Zheng (Y)

Department of Urology, the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Yiwu 223300, P. R. China.

Min Zhou (M)

Eye Center, the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 223300, P. R. China.
Zhejiang University-University of Edinburgh Institute (ZJU-UoE Institute), Zhejiang University School of Medicine, Zhejiang University, Haining 314400, P. R. China.
ORCID: 0000-0002-7319-9570

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Biocompatible Gallium Nanodots against...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux lourds › Gallium › Biocompatible Gallium Nanodots against...
questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Enterobacteriaceae › Escherichia › Escherichia coli › Biocompatible Gallium Nanodots against...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › Biocompatible Gallium Nanodots against...
questionsmedicales.fr › Bactéries › Biocompatible Gallium Nanodots against...
questionsmedicales.fr › Maladies de l'appareil respiratoire › Infections de l'appareil respiratoire › Pneumopathie infectieuse › Pneumopathie bactérienne › Biocompatible Gallium Nanodots against...
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies du foie › Abcès du foie › Biocompatible Gallium Nanodots against...
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité microbienne › Biocompatible Gallium Nanodots against...