Low-dose radiotherapy for greater trochanteric pain syndrome-a single-centre analysis.

Benign disease Greater trochanteric pain syndrome Low-dose radiation therapy Radiotherapy Trochanteric bursitis

Journal

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
ISSN: 1439-099X
Titre abrégé: Strahlenther Onkol
Pays: Germany
ID NLM: 8603469

Informations de publication

Date de publication:
14 Aug 2023
Historique:
received: 24 01 2023
accepted: 04 06 2023
medline: 15 8 2023
pubmed: 15 8 2023
entrez: 14 8 2023
Statut: aheadofprint

Résumé

To determine predictive factors associated with a good response (GR) to and efficacy of low-dose radiotherapy (LDRT) in patients with greater trochanteric pain syndrome (GTPS). Patients with GTPS were irradiated on a linear accelerator with 0.5-1.0 Gy per fraction to a total dose of 3.0-4.0 Gy per series. The endpoint was subjective good response (GR) to treatment 2 months after completion of the last LDRT series, defined as complete pain relief or marked improvement assessed using the von Pannewitz score. A positive response to steroid injection (SI) was defined as pain relief of at least 7 days. Patient and treatment-related characteristics were evaluated with respect to LDRT outcomes. Outcomes were assessed for 71 peritrochanteric spaces (PTSs; 65 patients, 48 females, with mean age of 63 [44-91] years). Prior SI had been given to 55 (77%) PTSs and 40 PTSs received two series of LDRT. Two months after completion of LDRT, GR was reported in 42 PTSs (59%). Two series of LDRT provided a significantly higher rate of GR than one series (72.5 vs. 42% PTSs, p = 0.015). Temporary pain relief after prior SI predicted GR to LDRT compared with PTSs which had not responded to SI (73 vs. 28% PTSs, p = 0.001). A regional structural abnormality, present in 34 PTSs (48%), was associated with a reduction of GR to LDRT (44 vs. 73% PTSs, p = 0.017). LDRT is an effective treatment for GTPS. Administration of two LDRT series, prior response to SI, and absence of structural abnormalities may predict significantly better treatment outcomes.

Identifiants

pubmed: 37580573
doi: 10.1007/s00066-023-02107-4
pii: 10.1007/s00066-023-02107-4
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© 2023. The Author(s).

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Auteurs

Michal Staruch (M)

Center for Radiation Oncology KSA-KSB, Kantonsspital Aarau, 5001, Aarau, Switzerland. michal.staruch@ksa.ch.
Clinical Trial Unit, Department of Clinical Research, University Hospital of Basel, University of Basel, 4031, Basel, Switzerland. michal.staruch@ksa.ch.
University of Bern, Hochschulstrasse 6, 3012, Bern, Switzerland. michal.staruch@ksa.ch.

Silvia Gomez (S)

Center for Radiation Oncology KSA-KSB, Kantonsspital Aarau, 5001, Aarau, Switzerland.

Susanne Rogers (S)

Center for Radiation Oncology KSA-KSB, Kantonsspital Aarau, 5001, Aarau, Switzerland.

Istvan Takacs (I)

Center for Radiation Oncology KSA-KSB, Kantonsspital Baden, 5404, Baden, Switzerland.

Thomas Kern (T)

Center for Radiation Oncology KSA-KSB, Kantonsspital Aarau, 5001, Aarau, Switzerland.

Sabine Adler (S)

Department of Rheumatology, Kantonsspital Aarau, 5001, Aarau, Switzerland.

Dieter Cadosch (D)

Department of Orthopaedic and Traumatology, Kantonsspital Aarau, 5001, Aarau, Switzerland.

Oliver Riesterer (O)

Center for Radiation Oncology KSA-KSB, Kantonsspital Aarau, 5001, Aarau, Switzerland.

Classifications MeSH