Twenty-Four-Month Blood Pressure Results After Renal Denervation Using Endovascular Ultrasound.


Journal

Journal of the American Heart Association
ISSN: 2047-9980
Titre abrégé: J Am Heart Assoc
Pays: England
ID NLM: 101580524

Informations de publication

Date de publication:
15 08 2023
Historique:
medline: 16 8 2023
pubmed: 15 8 2023
entrez: 15 8 2023
Statut: ppublish

Résumé

BACKGROUND Renal denervation has proven its efficacy to lower blood pressure in comparison to sham treatment in recent randomized clinical trials. Although there is a large body of evidence for the durability and safety of radiofrequency-based renal denervation, there are a paucity of data for endovascular ultrasound-based renal denervation (uRDN). We aimed to assess the long-term efficacy and safety of uRDN in a single-center cohort of patients. METHODS AND RESULTS Data from 2 previous studies on uRDN were pooled. Ambulatory 24-hour blood pressure measurements were taken before as well as 3, 6, 12, and 24 months after treatment with uRDN. A total of 130 patients (mean age 63±9 years, 24% women) underwent uRDN. After 3, 6, 12, and 24 months, systolic mean 24-hour ambulatory blood pressure values were reduced by 10±12, 10±14, 8±15, and 10±15 mm Hg, respectively, when compared with baseline (

Identifiants

pubmed: 37581398
doi: 10.1161/JAHA.123.030767
pmc: PMC10492948
doi:

Substances chimiques

Antihypertensive Agents 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e030767

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Auteurs

Sebastian Rosch (S)

Department of Cardiology Heart Center Leipzig at University of Leipzig Leipzig Germany.

Karl-Philipp Rommel (KP)

Department of Cardiology Heart Center Leipzig at University of Leipzig Leipzig Germany.

Stephan Blazek (S)

Department of Cardiology Heart Center Leipzig at University of Leipzig Leipzig Germany.

Karl-Patrik Kresoja (KP)

Department of Cardiology Heart Center Leipzig at University of Leipzig Leipzig Germany.

Anne Schöber (A)

Department of Cardiology Heart Center Leipzig at University of Leipzig Leipzig Germany.

Maximilian von Roeder (M)

Department of Cardiology Heart Center Leipzig at University of Leipzig Leipzig Germany.

Steffen Desch (S)

Department of Cardiology Heart Center Leipzig at University of Leipzig Leipzig Germany.

Holger Thiele (H)

Department of Cardiology Heart Center Leipzig at University of Leipzig Leipzig Germany.

Philipp Lurz (P)

Department of Cardiology Heart Center Leipzig at University of Leipzig Leipzig Germany.

Karl Fengler (K)

Department of Cardiology Heart Center Leipzig at University of Leipzig Leipzig Germany.

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