Reproductive Toxicity of Nanoparticles: A Comprehensive Review.

Nanomaterials Nanoparticles Nanosafety Nanotoxicology Reproductive toxicity Review

Journal

Current medicinal chemistry
ISSN: 1875-533X
Titre abrégé: Curr Med Chem
Pays: United Arab Emirates
ID NLM: 9440157

Informations de publication

Date de publication:
15 Aug 2023
Historique:
received: 10 04 2023
revised: 17 05 2023
accepted: 23 06 2023
medline: 15 8 2023
pubmed: 15 8 2023
entrez: 15 8 2023
Statut: aheadofprint

Résumé

The unique characteristics of nanoparticles (NPs) have captivated scientists in various fields of research. However, their safety profile has not been fully scrutinized. In this regard, the effects of NPs on the reproductive system of animals and humankind have been a matter of concern. In this article, we will review the potential reproductive toxicity of various types of NPs, including carbon nanomaterials, dendrimers, quantum dots, silica, gold, and magnetic nanoparticles, reported in the literature. We also mention some notable cases where NPs have elicited beneficial effects on the reproductive system. This review provides extensive insight into the effects of various NPs on sperm and ovum and the outcomes of their passage through blood-testis and placental barriers and accumulation in the reproductive organs.

Identifiants

DOI: 10.2174/0929867331666230815101141 PMID: 37581521
pubmed: 37581521
pii: CMC-EPUB-133573
doi: 10.2174/0929867331666230815101141
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Auteurs

Elaheh Mohammadi (E)

Students Research Committee, Faculty of pharmacy, Kerman University of Medical Sciences, Kerman, Iran.
Toxicology Research Center, Medical Basic Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Behzad Behnam (B)

Students Research Committee, Faculty of pharmacy, Kerman University of Medical Sciences, Kerman, Iran.
Pharmaceutics Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.
Herbal and Traditional Medicines Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Extremophile and Productive Microorganisms Research Center, Kerman University of Medical Science, Kerman, Iran.

Ahad Mokhtarzadeh (A)

Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.

Ramin Rezaee (R)

International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Ardavan Abiri (A)

Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.
Integrated Graduate Program in Physical and Engineering Biology, Yale University, New Haven, CT 06520, USA.

Mohammad Ramezani (M)

Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.

John P Giesy (JP)

Toxicology Centre, and Dept. Veterinary Biomedical Sciences, University of Saskatchewan, 10 Campus Drive, Saskatoon, SK S7N 5B4, Canada.
Dept. Environmental Sciences, Baylor University, Waco, TX, USA.

Amirhossein Sahebkar (A)

Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.

Classifications MeSH