Clinical and demographic characteristics of cervical cancer patients presenting at Parirenyatwa Hospital, Zimbabwe.

Clinicopathological profile Zimbabwe black African cervical cancer chemotherapy

Journal

African journal of reproductive health
ISSN: 1118-4841
Titre abrégé: Afr J Reprod Health
Pays: Nigeria
ID NLM: 9712263

Informations de publication

Date de publication:
Dec 2021
Historique:
medline: 1 12 2021
pubmed: 1 12 2021
entrez: 16 8 2023
Statut: ppublish

Résumé

Cervical cancer is the leading cause of cancer deaths in women in Africa, predominately due to late diagnosis. This study aims to identify risk factors, potential prognostic indicators, and optimal treatment modalities for Zimbabwean cervical cancer patients. Medical records for 1063 cervical cancer patients were reviewed for sociodemographic, clinical, treatment, and response data. All data were analysed using SPSS version 25. More than half of the cohort was pre-menopausal (63%) with low (2%) history of cervical cancer screening. Schistosoma ova were observed in 2.4% of the tumour specimens. More than 50% were diagnosed at stage 3 and later, with a high frequency of comorbidities (~68%). This study highlights a need for improving screening education and uptake in Zimbabwe. Moreover, the current data provides a dataset for understanding cervical cancer pathogenesis and treatment responses in an African cohort.

Identifiants

pubmed: 37585825
doi: 10.29063/ajrh2021/v25i6.11
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

99-109

Auteurs

Oppah Kuguyo (O)

University of Zimbabwe College of Health Sciences, Department of Clinical Pharmacology, Avondale, Harare, Zimbabwe.
University of Cape Town, Faculty of Health Sciences Department of Pathology, Human Genetics Division, 1 Anzio Rd, Observatory, Cape Town, South Africa.

Nomsa Tsikai (N)

of Zimbabwe College of Health Sciences, Department of Oncology, Avondale, Harare, Zimbabwe.

Senelisiwe Chipo Muradzikwa (SC)

University of Witwatersrand, Department of Statistics, Johannesburg, South Africa.

Kudakwashe Mhandire (K)

University of Cape Town, Faculty of Health Sciences Department of Pathology, Human Genetics Division, 1 Anzio Rd, Observatory, Cape Town, South Africa.

Charles Nhachi (C)

University of Zimbabwe College of Health Sciences, Department of Clinical Pharmacology, Avondale, Harare, Zimbabwe.

Thulani Magwali (T)

University of Zimbabwe College of Health Sciences, Department of Obstetrics and Gynaecology, Avondale, Harare, Zimbabwe.

Mugove G Madziyire (MG)

University of Zimbabwe College of Health Sciences, Department of Obstetrics and Gynaecology, Avondale, Harare, Zimbabwe.

Alice Matimba (A)

Advanced Courses and Scientific Conferences, Wellcome Genome Campus, Hinxton, UK.

Collet Dandara (C)

University of Cape Town, Faculty of Health Sciences Department of Pathology, Human Genetics Division, 1 Anzio Rd, Observatory, Cape Town, South Africa.
Institute of Infectious Diseases and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, South Africa.

Classifications MeSH