Experimental platforms for functional genomics in ticks.
Journal
Current opinion in insect science
ISSN: 2214-5753
Titre abrégé: Curr Opin Insect Sci
Pays: Netherlands
ID NLM: 101635599
Informations de publication
Date de publication:
10 2023
10 2023
Historique:
received:
20
04
2023
revised:
08
08
2023
accepted:
10
08
2023
medline:
9
10
2023
pubmed:
17
8
2023
entrez:
16
8
2023
Statut:
ppublish
Résumé
Ticks are blood-feeding ectoparasites that devastate cattle farming and are an omnipresent nuisance to pets and humans, posing a threat of pathogen transmission. Laboratory experimental models can be instrumental in the search for molecular targets of novel acaricides or vaccines. Mainly, though, the experimental models represent invaluable tools for broadening our basic understanding of key processes of tick blood-feeding physiology and vector competence. In order to understand the function of a single component within the full complexity of a feeding tick, genetic or biochemical interventions are used for systemic phenotypisation. In this work, we summarise current experimental modalities that represent powerful approaches for determining biological functions of tick molecular components.
Identifiants
pubmed: 37586557
pii: S2214-5745(23)00099-8
doi: 10.1016/j.cois.2023.101102
pii:
doi:
Substances chimiques
Vaccines
0
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
101102Informations de copyright
Copyright © 2023 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could influence the work reported in this paper.