To eat or not to eat: type 2 immunity controls food avoidance behavior.


Journal

Trends in immunology
ISSN: 1471-4981
Titre abrégé: Trends Immunol
Pays: England
ID NLM: 100966032

Informations de publication

Date de publication:
09 2023
Historique:
received: 28 07 2023
accepted: 28 07 2023
medline: 28 8 2023
pubmed: 17 8 2023
entrez: 16 8 2023
Statut: ppublish

Résumé

Growing evidence suggests that food allergies are regulated by neuroimmune interactions. However, the underlying molecular mechanisms remain unclear. Plum et al. and Florsheim et al. identify IgE-mediated mast cell activation, leukotrienes, and growth differentiating factor 15 (GDF15) as key regulators of the avoidance response to food allergens in mice.

Identifiants

pubmed: 37586904
pii: S1471-4906(23)00154-0
doi: 10.1016/j.it.2023.07.007
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

665-667

Subventions

Organisme : Howard Hughes Medical Institute
Pays : United States

Commentaires et corrections

Type : CommentOn
Type : CommentOn

Informations de copyright

Copyright © 2023 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests The authors declare no conflicts of interests.

Auteurs

Albana L Kodra (AL)

Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA. Electronic address: akodra@rockefeller.edu.

Daniel Mucida (D)

Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA; Howard Hughes Medical Institute, The Rockefeller University, New York, NY, USA. Electronic address: mucida@rockefeller.edu.

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Classifications MeSH