Mesenchymal stem cell engineering by ARCA analog-capped mRNA.

ARCA-cap analogs MT: oligonucleotides: therapies and applications immune response mRNA transfection mesenchymal stem cells metabolic activity

Journal

Molecular therapy. Nucleic acids
ISSN: 2162-2531
Titre abrégé: Mol Ther Nucleic Acids
Pays: United States
ID NLM: 101581621

Informations de publication

Date de publication:
12 Sep 2023
Historique:
received: 11 01 2023
accepted: 11 07 2023
medline: 17 8 2023
pubmed: 17 8 2023
entrez: 17 8 2023
Statut: epublish

Résumé

We previously have shown that mRNA-based engineering may enhance mesenchymal stem cell (MSC) trafficking. However, optimal conditions for

Identifiants

pubmed: 37588684
doi: 10.1016/j.omtn.2023.07.006
pii: S2162-2531(23)00179-8
pmc: PMC10425852
doi:

Types de publication

Journal Article

Langues

eng

Pagination

454-468

Informations de copyright

© 2023 The Authors.

Déclaration de conflit d'intérêts

M.J. is a co-founder of IntraART, Ti-com, and ART-EX, but they are not related to the current manuscript.

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Auteurs

Anna Andrzejewska (A)

NeuroRepair Department, Mossakowski Medical Research Institute, Polish Academy of Sciences, 02-106 Warsaw, Poland.
Center for Advanced Imaging Research, Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland, Baltimore, MD 21201, USA.

Renata Grzela (R)

Division of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, 02-093 Warsaw, Poland.
Interdisciplinary Laboratory of Molecular Biology and Biophysics, Centre of New Technologies, University of Warsaw, 02-097 Warsaw, Poland.

Anna Stankiewicz-Drogon (A)

Division of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, 02-093 Warsaw, Poland.

Piotr Rogujski (P)

NeuroRepair Department, Mossakowski Medical Research Institute, Polish Academy of Sciences, 02-106 Warsaw, Poland.

Siranjeevi Nagaraj (S)

Interdisciplinary Laboratory of Molecular Biology and Biophysics, Centre of New Technologies, University of Warsaw, 02-097 Warsaw, Poland.

Edward Darzynkiewicz (E)

Division of Biophysics, Institute of Experimental Physics, Faculty of Physics, University of Warsaw, 02-093 Warsaw, Poland.
Interdisciplinary Laboratory of Molecular Biology and Biophysics, Centre of New Technologies, University of Warsaw, 02-097 Warsaw, Poland.

Barbara Lukomska (B)

NeuroRepair Department, Mossakowski Medical Research Institute, Polish Academy of Sciences, 02-106 Warsaw, Poland.

Miroslaw Janowski (M)

Center for Advanced Imaging Research, Department of Diagnostic Radiology and Nuclear Medicine, University of Maryland, Baltimore, MD 21201, USA.
Tumor Immunology and Immunotherapy Program, University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, MD 21201, USA.

Classifications MeSH