High-flow nasal oxygenation during gastrointestinal endoscopy. Systematic review and meta-analysis.

complications digestive system endoscopy gastrointestinal endoscopy hypoxia oxygen inhalation therapy

Journal

BJA open
ISSN: 2772-6096
Titre abrégé: BJA Open
Pays: England
ID NLM: 9918419157906676

Informations de publication

Date de publication:
Dec 2022
Historique:
received: 12 01 2022
accepted: 14 09 2022
medline: 17 8 2023
pubmed: 17 8 2023
entrez: 17 8 2023
Statut: epublish

Résumé

The use of high-flow nasal oxygen (HFNO) has the potential to improve patient safety by limiting hypoxaemia during gastrointestinal endoscopy. The degree of benefit is not adequately established. English language literature searches of PubMed, Scopus, Web of Science, and Cochrane Library electronic databases were performed to identify randomised controlled trials comparing HFNO and conventional oxygen therapy (COT) for patients undergoing gastrointestinal endoscopy under deep sedation. The primary endpoint was the incidence of hypoxic events observed during endoscopic procedures. The secondary endpoints were the incidence of recourse to rescue manoeuvres, procedure interruption, and adverse events. A meta-analysis and a A total of 2867 patients from six randomised controlled trials were considered. Desaturation was observed in 5.2% and 27.2% of patients receiving HFNO and COT, respectively. Desaturation <90% was observed in 1.8% and 12.6% of the patients receiving HFNO and COT, respectively. In the subgroup analysis, desaturation occurrence was lower during HFNO than during COT in non-obese patients (2.2% The evidence reviewed suggests that compared with COT, HFNO has fewer hypoxaemic events during gastrointestinal endoscopy, but this may not apply to all patients and clinical scenarios.

Sections du résumé

Background UNASSIGNED
The use of high-flow nasal oxygen (HFNO) has the potential to improve patient safety by limiting hypoxaemia during gastrointestinal endoscopy. The degree of benefit is not adequately established.
Methods UNASSIGNED
English language literature searches of PubMed, Scopus, Web of Science, and Cochrane Library electronic databases were performed to identify randomised controlled trials comparing HFNO and conventional oxygen therapy (COT) for patients undergoing gastrointestinal endoscopy under deep sedation. The primary endpoint was the incidence of hypoxic events observed during endoscopic procedures. The secondary endpoints were the incidence of recourse to rescue manoeuvres, procedure interruption, and adverse events. A meta-analysis and a
Results UNASSIGNED
A total of 2867 patients from six randomised controlled trials were considered. Desaturation was observed in 5.2% and 27.2% of patients receiving HFNO and COT, respectively. Desaturation <90% was observed in 1.8% and 12.6% of the patients receiving HFNO and COT, respectively. In the subgroup analysis, desaturation occurrence was lower during HFNO than during COT in non-obese patients (2.2%
Conclusions UNASSIGNED
The evidence reviewed suggests that compared with COT, HFNO has fewer hypoxaemic events during gastrointestinal endoscopy, but this may not apply to all patients and clinical scenarios.

Identifiants

pubmed: 37588780
doi: 10.1016/j.bjao.2022.100098
pii: S2772-6096(22)00097-1
pmc: PMC10430836
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

100098

Informations de copyright

© 2022 The Author(s).

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Auteurs

Michele Carron (M)

Department of Medicine - DIMED, Section of Anaesthesiology and Intensive Care, University of Padua, Padua, Italy.

Enrico Tamburini (E)

Department of Medicine - DIMED, Section of Anaesthesiology and Intensive Care, University of Padua, Padua, Italy.

Bijan Safaee Fakhr (B)

Department of Medicine - DIMED, Section of Anaesthesiology and Intensive Care, University of Padua, Padua, Italy.

Alessandro De Cassai (A)

Institute of Anaesthesia and Intensive Care - Azienda Ospedale Università Padova, Padua, Italy.

Federico Linassi (F)

Department of Anaesthesia and Intensive Care, Ca' Foncello Treviso Regional Hospital, Piazzale Ospedale 1,Treviso, Italy.

Paolo Navalesi (P)

Department of Medicine - DIMED, Section of Anaesthesiology and Intensive Care, University of Padua, Padua, Italy.

Classifications MeSH