The onchocerciasis hypothesis of nodding syndrome.
Journal
PLoS neglected tropical diseases
ISSN: 1935-2735
Titre abrégé: PLoS Negl Trop Dis
Pays: United States
ID NLM: 101291488
Informations de publication
Date de publication:
08 2023
08 2023
Historique:
medline:
21
8
2023
pubmed:
17
8
2023
entrez:
17
8
2023
Statut:
epublish
Résumé
Nodding syndrome (NS) is a phenotypic presentation of onchocerciasis-associated epilepsy (OAE). OAE is an important public health problem in areas with high ongoing Onchocerca volvulus transmission. OAE, including NS, is preventable by strengthening onchocerciasis elimination programs. The presence of tau in OAE postmortem brains could be the consequence of neuroinflammation directly or indirectly induced by O. volvulus. Omics research is needed to investigate whether O. volvulus worms contain a neurotropic virus.
Identifiants
pubmed: 37590176
doi: 10.1371/journal.pntd.0011523
pii: PNTD-D-23-00706
pmc: PMC10434893
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0011523Informations de copyright
Copyright: © 2023 Colebunders et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Brain. 2023 Mar 1;146(3):954-967
pubmed: 35411378
PLoS Negl Trop Dis. 2009 Jun 16;3(6):e461
pubmed: 19529767
Neurol Neuroimmunol Neuroinflamm. 2022 Dec 21;10(2):
pubmed: 36543539
Trans R Soc Trop Med Hyg. 2002 Sep-Oct;96(5):537-41
pubmed: 12474484
Epileptic Disord. 2020 Jun 1;22(3):301-308
pubmed: 32540799
Pathogens. 2021 May 14;10(5):
pubmed: 34068976
BMJ Open. 2014 Nov 04;4(11):e006195
pubmed: 25371417
Open Forum Infect Dis. 2020 Jun 02;7(6):ofaa206
pubmed: 32587878
J Neuropathol Exp Neurol. 2019 Nov 1;78(11):1049-1058
pubmed: 31553445
Pathogens. 2021 Nov 09;10(11):
pubmed: 34832607
Seizure. 2018 Dec;63:93-101
pubmed: 30468964
Tropenmed Parasitol. 1976 Jun;27(2):123-32
pubmed: 941247
Lancet Glob Health. 2023 Aug;11(8):e1260-e1268
pubmed: 37474232
Trends Parasitol. 2023 Feb;39(2):126-138
pubmed: 36528471
Afr Health Sci. 2013 Jun;13(2):529-40
pubmed: 24235964
PLoS Negl Trop Dis. 2023 Jun 28;17(6):e0011178
pubmed: 37379350
Immunopharmacol Immunotoxicol. 2012 Jun;34(3):477-83
pubmed: 22564175
Infect Dis Poverty. 2020 Mar 2;9(1):12
pubmed: 32114979